Crude drug sample data base

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Crude drug name

Market name川牛膝
Formal name川牛膝
Japanese nameせんごしつ, Sengoshitsu
Vernacular nameChuanniuxi
Latin nameCyathulae Radix
English nameCyathula Root
Original plant nameCyathula officinalis Kuan
Family nameAmaranthaceae
Used partClassificationPlant origin
Sub classification root
Collection informationPeople's Republic of China, Chengdu, Hehuachi Market, Chengdu
Collection date1986/06/14
CollectorTsuneo Namba, et al.
TMPW No.4644

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
30.572815
104.06680099999994
Collection information
People's Republic of China,Chengdu
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name牛膝(中国産), Niuxi, Achyranthis Radix (JP18), Achyranthis Bidentatae Radix (CP2020), Achyranthes Root (JP18), Two-toothed Achyranthes Root (CP2020)
Synonyms懐牛膝
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Original plant nameAchyranthes bidentata Blume, Achyranthes fauriei H. Léveillé et Vaniot1, (Hinanainokozuchi1)
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Family nameAmaranthaceae
Used partroot
Quality for selectionGood Niuxi is long, enlarged, dense, soft and yellowish-white. The Chinese Niuxi is high quality. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs a diuretic and painkiller, for removing blood stasis and inducing menstruation, Niuxi is applied for menstrual disorder, blood stasis, arthritis of lumbar and knee joints, paralysis, edema and oliguria.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for invigorating blood circulation
Beneficial effect[Property and Flavor] Neutral; bitter, sweet and sour.
[Meridian Tropism] Liver and kidney meridians.
[Actions] To expel stasis to unblock the meridian, tonify liver-kidney, strengthen sinew and bone, disinhibit urine and relieve stranguria, and conduct blood downward.
[Indications] Amenorrhea, dysmenorrhea, limp aching in the lower back and knees, lack of strength of sinew and bone, stranguria, edema, headache, dizziness, toothahe, mouth sore, hematemesis, epistaxis.
Chemical constituentTriterpenoid saponins
(*C1):
Oleanolic acidをゲニンとするサポニン/ saponin, whose genin is Oleanolic acid

Sterols
(*C2):
beta-sitosterol,stigamasterol

Ecdysones & Phytoecdysones
A. bidentata, A. longifolia (*C1):
Ecdysterone, Inokosterone
C. officinalis (*C1):
Cyasterone

Others
(*C2):
K-Succinate,K-Oxalate,gamma-Aminobutyric acid

Chemical structure





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Pharmacological effectAntiallergy, antiosteoporosis.
DNA sequenceTraditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseMenorrhalgia, Extension of menstrual cycle, Amenorrhea, Intra-abdominal tumor, Dystocia, Retention of the placenta, Swelling and pain due to contusion, Swelling and pain of joint, Heaviness and powerlessness in lumber and knee, Lower back pain, Edema, Urodynia, Dysuria, Hematuria, Nasal hemorrhage, Hematemesis, Hemoptysis, Swelling and pain of the root of tooth, Stomatitis, Bleeding from root of tooth, Headache, Vertigo, Stagger
FormulationAnzanto, Ishoho, Kamishimotsuto, Kamihassento, Goshajinkigan, Jokinritsuansan, Sesshoin, Sokeikakketsuto, Daibyakuchuin, Daibofuto, Dokkatsukiseito, Hointo
Related drugsChuanniuxi, Tuniuxi and Wagoshitsu (Japan)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 27-29.
C2)Outline of Pharmacognosy, a Textbook, p 312.
Remarks- Sengoshitsu (Chuanniuxi, Cyathulae Radix) is the root of Cyathula officinalis Kuan of family Amaranthaceae. It is both cultivated and found wild in Sichuan Province. It is listed in the Pharmacopoeia of the People's Republic of China (2020 edi.). It is used for activating blood and restoring menstruation, strengthening joints, and curing strangury by inducing diuresis. It is applied to treat amenorrhea with mass formation in the abdomen, retention of placenta caused by stagnation of blood stasis, palsy of joints, weakness in the legs and muscle, hematuria and bruises. Chuanniuxi is also called Quantianniuxi, Mixinniuxi, Yunniuxi, Guainiuxi and Tianniuxi. Many plants of genus Achyranthes are used as Nuixi locally, which are called Tuniuxi.

- The Japanese Pharmacopoeia 18th edi. defines the root of Achyranthes bidentataor A. fauriei (Jap. name: Hinatainokozuchi) as Goshitsu (Niuxi). Goshitsu cultivated in Tochigi and Nara prefectures was called Hitachi-goshitsu and wild Goshitsu was called Yabu-goshitsu. At present, no Japanese Goshitsu is produced.
Botanically, Hinatainokozuchi is a variant of A. bidentata (= A. japonica Nakai), (Jap. name: Inokozuchi or Hikageinokozuchi). Therefore, the nomenclature of Hinatainokozuchi is A. bidentata Blume var. tomentosa (Honda) H. Hara.
Last renewal date2022/07/29