Crude drug sample data base

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Crude drug name

Market name常山
Formal name常山
Japanese nameじょうざん, Jōzan
Vernacular nameChangshan
Latin nameDichroae Radix (CP)
English nameAntifeverile Dichroa Root (CP)
Original plant nameDichroa febrifuga Lour., (Jōzan'ajisai)
Family nameSaxifragaceae
Used partClassificationPlant origin
Sub classification root
Collection informationHong Kong, Wing Tai Hong Medicine Co.,Ltd.
Collection date1974/12/25
TMPW No.486

Scientific information data base

Common name常山, Changshan, Dichroae Radix (CP2020), Antifeverile Dichroa Root (CP2020)
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Original plant nameDichroa febrifuga Loureiro, (Jōzan'ajisai)
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Family nameSaxifragaceae
Used partroot
Quality for selectionGood Changshan is the root of Kokusagi (Jap. name), a small tree and tinged with yellow.(NI)
Official compendiumCP (2020 ed.)
Clinical applicationChangshan is an important drug for malaria. As an antifebrile and phlegm-raising, it is applied for various malarial related diseases, hypochondriac distention, and accumulation of persistent phlegm.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for vomit
Beneficial effect[Property and Flavor] Cold; bitter, pungent; toxic.
[Meridian Tropism] Lung, liver and heart meridians.
[Actions] To induce vomiting of phlegm and slobber, and interrupt malaria.
[Indications] Phlegm-fluid retention, stuffiness in the chest and the diaphragm, and malaria.
Chemical constituentCoumarins
(*C1):
Umbelliferone

Alkaloids
アルカロイド約 / alkaloids about 0.1% (*C1):
alpha-Dichroine, beta-Dichroine, gamma-Dichroine, Dichroidine, Febrifugine, Isofebrifugine

Other nitrogen compounds
(*C1):
4-Quinazolone

Chemical structure


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Pharmacological effectAntimalaria (water leaching, beta-dichroine, gamma-dichroine). Cardiotonic and antipyretic (decoction).
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseFeeling of pressure in the chest, Impossible to expectorate sputum, Alternating cold and fever
FormulationKyugyakuto, Keishikyoshakuyakukashokushitsuryukotsuboreikyugyakuto, Jobinto, Boreito
Related drugs (see "Remarks")
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 146-149.
RemarksThere are many different plants under the name of Changshan.
- Japanese Changshan and Syūjōzan: The root of Orixa japonica Thunb. of family Rutaceae (Jap. name: Kokusagi).
- Hakujōzan: The root of family Rubiaceae, Mussaenda parviflora Miq. or M. divaricata Hutch.
- Kaishūjōzan: The root of Clerodendron trichotomum Thunb. of family Verbenaceae (Jap. name: Kusagi).
- Dojōzan: The root of Hydrangea aspera Buch.-Ham. ex D.Don or H. strigosa Rehd. of family Saxifragaceae and other congeners. Dojōzan also includes the roots of Symplocos chinensis Druce of family Symplocaceae (Jap. name: Taiwansawahutagi), Vitex negundo L. and V. cannabifolia Sieb. et Zucc. (Jap. name: Ninjinboku) of family Verbenaceae.
- Sanjōzan: The root of Berberis sibirica Pallas of family Berberidaceae and other Berberis species.
Last renewal date2021/09/27