Crude drug sample data base

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Crude drug name

Market name常山
Formal name常山
Japanese nameじょうざん, Jōzan
Vernacular nameChangshan
Latin nameDichroae Radix (CP)
English nameAntifeverile Dichroa Root (CP)
Original plant nameDichroa febrifuga Lour., (Jōzan'ajisai)
Family nameSaxifragaceae
Used partClassificationPlant origin
Sub classification root
Production area informationPeople's Republic of China, Hong Kong Special Administrative Region
Collection informationJapan, Niigata Pref., Uchida Wakanyaku Co., Ltd.
Collection date1985/02/15
CollectorMasayuki Mikage
TMPW No.5044

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
22.2799907
114.15879829999994
Production area information
People's Republic of China,Hong Kong Special Administrative Region
https://ethmed.toyama-wakan.net/img/pin_san.png
37.9025518
139.02309460000004
Collection information
Japan,Niigata Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name常山, Changshan, Dichroae Radix (CP2020), Antifeverile Dichroa Root (CP2020)
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Original plant nameDichroa febrifuga Loureiro, (Jōzan'ajisai)
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Family nameSaxifragaceae
Used partroot
Quality for selectionGood Changshan is the root of Kokusagi (Jap. name), a small tree and tinged with yellow.(NI)
Official compendiumCP (2020 ed.)
Clinical applicationChangshan is an important drug for malaria. As an antifebrile and phlegm-raising, it is applied for various malarial related diseases, hypochondriac distention, and accumulation of persistent phlegm.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Drugs for vomit
Beneficial effect[Property and Flavor] Cold; bitter, pungent; toxic.
[Meridian Tropism] Lung, liver and heart meridians.
[Actions] To induce vomiting of phlegm and slobber, and interrupt malaria.
[Indications] Phlegm-fluid retention, stuffiness in the chest and the diaphragm, and malaria.
Chemical constituentCoumarins
(*C1):
Umbelliferone

Alkaloids
アルカロイド約 / alkaloids about 0.1% (*C1):
alpha-Dichroine, beta-Dichroine, gamma-Dichroine, Dichroidine, Febrifugine, Isofebrifugine

Other nitrogen compounds
(*C1):
4-Quinazolone

Chemical structure


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Pharmacological effectAntimalaria (water leaching, beta-dichroine, gamma-dichroine). Cardiotonic and antipyretic (decoction).
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseaseFeeling of pressure in the chest, Impossible to expectorate sputum, Alternating cold and fever
FormulationKyugyakuto, Keishikyoshakuyakukashokushitsuryukotsuboreikyugyakuto, Jobinto, Boreito
Related drugs (see "Remarks")
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 146-149.
RemarksThere are many different plants under the name of Changshan.
- Japanese Changshan and Syūjōzan: The root of Orixa japonica Thunb. of family Rutaceae (Jap. name: Kokusagi).
- Hakujōzan: The root of family Rubiaceae, Mussaenda parviflora Miq. or M. divaricata Hutch.
- Kaishūjōzan: The root of Clerodendron trichotomum Thunb. of family Verbenaceae (Jap. name: Kusagi).
- Dojōzan: The root of Hydrangea aspera Buch.-Ham. ex D.Don or H. strigosa Rehd. of family Saxifragaceae and other congeners. Dojōzan also includes the roots of Symplocos chinensis Druce of family Symplocaceae (Jap. name: Taiwansawahutagi), Vitex negundo L. and V. cannabifolia Sieb. et Zucc. (Jap. name: Ninjinboku) of family Verbenaceae.
- Sanjōzan: The root of Berberis sibirica Pallas of family Berberidaceae and other Berberis species.
Last renewal date2021/09/27
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