Crude drug sample data base

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Crude drug name

Market name沈香片
Formal name沈香
Japanese nameじんこう, Jinkō
Vernacular nameChenxiang pian
Latin nameAquilariae Resinatum Lignum (Non-JPS), Aqnilariae Lignun Resinatum (CP)
English nameAgarwood (Non-JPS), Chinese Eaglewood Wood (CP)
Original plant nameAquilaria agallocha Roxb., or other species of the same genus
Family nameThymelaeaceae
Used partClassificationPlant origin
Sub classification wood
Collection informationHong Kong, Qiao Xin Can Rong Joekhong
Collection date1986/11/10
TMPW No.5408

Scientific information data base

Common name沈香, Chenxiang, Aquilariae Resinatum Lignum (Non-JPS2022), Aquilariae Lignum Resinatum (CP2020), Agarwood (Non-JPS2022), Chinese Eaglewood Wood (CP2020)
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Original plant nameAquilaria agallocha Roxburgh, Aquilaria crassna Pierre ex Lecomte, Aquilaria malaccensis Lamarck, Aquilaria sinensis Gilg or Aquilaria filaria Merrill
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Family nameThymelaeaceae
Used partwood, especially splint wood containing penetrated black resin
Quality for selectionIt should be firm, blackish in color, glossy on the surface, submerged in water, easy to burn and fragrant. (TN)
Official compendiumNon-JPS (2022), CP (2020 ed.)
Clinical applicationAs an antivomiting, antitussive, and sedative, it is applied to treat hysteria, qi stagnation, vomiting, asthma, and cardiac weakness. It is generally used as a fragrance material for high-grade incense sticks and combined incense.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Carminatives for regulating flow of Qi
Beneficial effect[Property and Flavor] Mild warm; pungent and bitter.
[Meridian Tropism] Spleen, stomach and kidney meridians.
[Actions] To move qi and relieve pain, warm the middle energizer to check vomiting, absorb qi to relieve panting.
[Indications] Distention, oppression and pain in the chest and the abdomen, vomiting and hiccup caused by stomach cold, panting caused by qi counterflow caused by kidney deficiency.
Chemical constituentSesquiterpenoids
(*C1):
Agarospiol, Agarol, Agarofurans
(*C2-7):
alpha-Agarofuran, (-)-10-Epi-gamma-eudesmol, Jinkoh-eremol, Kusunol, Jinkohol, JinkoholⅡ, Dihydrokaranone, Agarospirol, Oxo-agarospirol

Phenylpropanoids
(*C1):
Hydrocinnamic acid, p-Methoxyhydrocinnamic acid

gamma-Pyrone derivatives
(*C1):
Agaroterol

Other aromatic derivatives
(*C1):
Benzylacetone, p-Methoxybenzylacetone

Chemical structure




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Pharmacological effectAnalgesia, sedation (essential oil), antibacterial (decoction: Mycobacterium tuberculosis, Salmonella typhi, Shigella).
DNA sequenceY15149
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseasePain due to flatulence of hypochondrium, Feeling of pressure in the chest, Chest pain, Vomitting, Hiccup, Dyspnea, Rapid breathing, Hysteria
FormulationKagenshosaikoto, Jinkokokito, Zenshikunshito, Daibyakuchuin, Chokoshiteito, Tokiyoketsuto, Hojinto
Related drugsJiananxian (Jialu)
ReferencesNon-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 181-184.
C2-7)Shoyakugaku Zasshi,40(3), 252, 259, 266, 271, 275(1986); 41(2), 142(1987).
C8)Shosoin Medicaments, pp132-135, 147-148.
Remarks- The original plant of Chenxiang includes Aquilaria agallocha Roxb. (products of India, Malaysia, Vietnam and Cambodia), A. malaccensis Lam. (Malaysia), A. baillonii Pierre (Cambodia), A. crassna Pierre (Cambodia and Vietnam) and A. sinensis (Lour.) Gilg (China). Japan imports a large amount from Singapore and Vietnam. They are identified by the composition of sesquiterpenoids as follows.: Singapore I-type (SI-type) contains much jinkohol and jinkohol II. SingaporeII-type (SII-type) does not contain them. Vietnam type (V-type) does not contain jinkohol nor jinkohol II but much dihydrokaranone and oxo-agarospirol (C2, C5). Chinese Chenxiang resembles V-type, which has a high content of oxo-agarospirol (C3). The allied species Kanankō (伽南香, Jap. name), which is also called Kyara (伽羅), has been said to be superior to Chenxiang. It contains chromones which are not found in Chenxiang. In addition, it has higher contents of benzene extract (C5) and acetone extract (C7).
- A. sinensis produced in China is listed in the Chinese Pharmacopoeia (2020) and is called Dojinkō, Kainanjinkō and etc. It is mostly imported into Japan for use as incense.
- The medicines stored in the Shosoin Repository include Jinkō and Zōjin, Zensenkō (Kōjin), and Ōjukukō (Ranjatai). They have no sesquiterpenoids nor 1-8diethylchromone nor phenyethylchromone. Therefore, it is attested that their origins are closely related to Chenxiang produced in northern Indochina such as Vietnam (C8). Thus, in the middle of the 8th century, items similar to those on the market today were introduced to Japan.
Last renewal date2022/07/20