Crude drug sample data base
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Scientific information data base
Common name | 牛膝(日本産), (Wa)Goshitsu, Achyranthis Radix (JP18), Achyranthes Root (JP18) | |||||
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Synonyms | 常陸牛膝,薮牛膝 | |||||
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Original plant name | Achyranthes fauriei H. Léveillé et Vaniot, (Hinatanoinokozuchi) | |||||
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Family name | Amaranthaceae | |||||
Used part | root | |||||
Quality for selection | Good Niuxi is long, fat, dense, soft and yellowish-white. (TN) | |||||
Official compendium | JP XVIII | |||||
Clinical application | As a diuretic and painkiller, for removing blood stasis and inducing menstruation, Niuxi is applied for menstrual disorder, blood stasis, arthritis of lumbar and knee joints, paralysis, edema and oliguria. | |||||
Medical system | Traditional Chinese medicine | |||||
Chemical constituent | Triterpenoid saponins (*C1): Oleanolic acidをゲニンとするサポニン/saponin, whose genin is Oeanolic acid Sterols (*C2): beta-Sitosterol,Stigmasterwl Ecdysones & Phytoecdysones A. fauriei (*C1): Ecdysterone, Inokosterone, Epiecdysterone, Rubrosterone A. japonica,A. longifolia (*C1): Ecdysterone, Inokosterone Amino acids (*C2): gamma-Aminobutyric acid Others (*C2): K-Succinate,K-Oxalate | |||||
Chemical structure |
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Pharmacological effect | Antiallergy, antiosteoporosis. | |||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
Disease | Menorrhalgia, Extension of menstrual cycle, Amenorrhea, Intra-abdominal tumor, Dystocia, Retention of the placenta, Swelling and pain due to contusion, Swelling and pain of joint, Heaviness and powerlessness in lumber and knee, Lower back pain, Edema, Urodynia, Dysuria, Hematuria, Nasal hemorrhage, Hematemesis, Hemoptysis, Swelling and pain of the root of tooth, Stomatitis, Bleeding from root of tooth, Headache, Vertigo, Stagger | |||||
Formulation | Anzanto, Ishoho, Kamishimotsuto, Kamihassento, Goshajinkigan, Jokinritsuansan, Sesshoin, Sokeikakketsuto, Daibyakuchuin, Daibofuto, Dokkatsukiseito, Hointo | |||||
Related drugs | Niuxi (Huainiuxi), Chuanniuxi andTuniuxi | |||||
References | JP18: The 18th edition of the Japanese Pharmacopoeia. C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 27-29. C2) Outline of Pharmacognosy, a Textbook,p312. | |||||
Remarks | The Japanese Pharmacopoeia 18th edi. defines the root of Achyranthes bidentataor A. fauriei (Jap. name: Hinatainokozuchi) as Goshitsu (Niuxi). Goshitsu cultivated in Tochigi and Nara prefectures was called Hitachi-goshitsu and wild Goshitsu was called Yabu-goshitsu. At present, no Japanese Goshitsu is produced. Botanically, Hinatainokozuchi is a variant of A. bidentata (= A. japonica Nakai), (Jap. name: Inokozuchi or Hikageinokozuchi). Therefore, the nomenclature of Hinatainokozuchi is A. bidentata Blume var. tomentosa (Honda) H. Hara. | |||||
Last renewal date | 2021/09/27 | |||||