Crude drug sample data base

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Crude drug name

Market name和牛膝
Formal name和牛膝
Japanese nameわごしつ, Wagoshitsu
Vernacular nameWagoshitsu
Latin nameAchyranthis Radix (JP)
English nameAchyranthes Root (JP)
Original plant nameAchyranthes fauriei Leveille et Vaniot,  (Hinatanoinokozuchi)
Family nameAmaranthaceae
Used partClassificationPlant origin
Sub classification root
Production area informationJapan
TMPW No.652

Scientific information data base

Common name牛膝(日本産), (Wa)Goshitsu, Achyranthis Radix (JP18), Achyranthes Root (JP18)
Synonyms常陸牛膝,薮牛膝
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Original plant nameAchyranthes fauriei H. Léveillé et Vaniot, (Hinatanoinokozuchi)
original plant image
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Family nameAmaranthaceae
Used partroot
Quality for selectionGood Niuxi is long, fat, dense, soft and yellowish-white. (TN)
Official compendiumJP XVIII
Clinical applicationAs a diuretic and painkiller, for removing blood stasis and inducing menstruation, Niuxi is applied for menstrual disorder, blood stasis, arthritis of lumbar and knee joints, paralysis, edema and oliguria.
Medical systemTraditional Chinese medicine
Chemical constituentTriterpenoid saponins
(*C1):
Oleanolic acidをゲニンとするサポニン/saponin, whose genin is Oeanolic acid

Sterols
(*C2):
beta-Sitosterol,Stigmasterwl

Ecdysones & Phytoecdysones
A. fauriei (*C1):
Ecdysterone, Inokosterone, Epiecdysterone, Rubrosterone
A. japonicaA. longifolia (*C1):
Ecdysterone, Inokosterone

Amino acids
(*C2):
gamma-Aminobutyric acid

Others
(*C2):
K-Succinate,K-Oxalate

Chemical structure




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Pharmacological effectAntiallergy, antiosteoporosis.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseMenorrhalgia, Extension of menstrual cycle, Amenorrhea, Intra-abdominal tumor, Dystocia, Retention of the placenta, Swelling and pain due to contusion, Swelling and pain of joint, Heaviness and powerlessness in lumber and knee, Lower back pain, Edema, Urodynia, Dysuria, Hematuria, Nasal hemorrhage, Hematemesis, Hemoptysis, Swelling and pain of the root of tooth, Stomatitis, Bleeding from root of tooth, Headache, Vertigo, Stagger
FormulationAnzanto, Ishoho, Kamishimotsuto, Kamihassento, Goshajinkigan, Jokinritsuansan, Sesshoin, Sokeikakketsuto, Daibyakuchuin, Daibofuto, Dokkatsukiseito, Hointo
Related drugsNiuxi (Huainiuxi), Chuanniuxi andTuniuxi
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 27-29.
C2) Outline of Pharmacognosy, a Textbook,p312.
RemarksThe Japanese Pharmacopoeia 18th edi. defines the root of Achyranthes bidentataor A. fauriei (Jap. name: Hinatainokozuchi) as Goshitsu (Niuxi). Goshitsu cultivated in Tochigi and Nara prefectures was called Hitachi-goshitsu and wild Goshitsu was called Yabu-goshitsu. At present, no Japanese Goshitsu is produced.
Botanically, Hinatainokozuchi is a variant of A. bidentata (= A. japonica Nakai), (Jap. name: Inokozuchi or Hikageinokozuchi). Therefore, the nomenclature of Hinatainokozuchi is A. bidentata Blume var. tomentosa (Honda) H. Hara.
Last renewal date2021/09/27