Crude drug sample data base

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Crude drug name

Market nameアロエ
Formal nameアロエ
Japanese nameあろえ, Aloe
Latin nameAloe (JP), (CP)
English nameAloe (JP), (CP)
Original plant nameAloe ferox Miller, or hybrids of the species with Aloe africana Miller or Aloe spicata Baker
Family nameLiliaceae
Used partClassificationPlant origin
Sub classification leaf juice
Collection informationJapan, Osaka Pref., Nippon Funmatsu Yakuhin Co., Ltd.
Collection date1985/11/16
CollectorTsuneo Namba
TMPW No.8028

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base

Common nameアロエ・蘆薈, Luhui, Aloe (JP18, CP2020), Aloe (JP18), Aloes (CP2020)
Synonymsケープ・アロエ (Cape Aloes), 透明アロエ (Aloe Lucida)
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Original plant nameAloe ferox Miller, mainly or of interspecific hybrids of the species with Aloe africana Miller or Aloe spicata Baker
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Family nameLiliaceae
Used partleaf juice
Quality for selectionGood Luhui is solid and dark brown. The cross- section is smooth and has glassy luster. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationLuhui is widely used for chronic constipation as a laxative. It is applied for apepsia and chronic gastric catarrh as a stomachic in small doses. Since luhui doesn't contain tannin, it doesn't cause constipation after laxation. In large doses, it congests intestinal wall and pelvic lumen. Therefore, it must be used carefully during menstrual or pregnancy period and hemorrhoid.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Purgatives
Beneficial effect[Property and Flavor] Cold; bitter
[Meridian Tropism] Liver, stomach and large intestine meridians.
[Actions] To purge the intestines, open the bowels, clear the liver, purge fire, kill worms and relieve malnutrition.
[Indications] Heat bind constipation, seizures and convulsions, infantile malnutrition with food retention; topically for tinea and sore.
Chemical constituentPolysaccharides
糖タンパク / glycoprotein
Cape Aloes, Socotrine Aloes, Curacao Aloes (*C1):
Loctin A

Anthraquinones
Cape Aloes, Socotrine Aloes, Curacao Aloes (*C1,C2):
Barbaloin, Aloinoside A, Aloinoside B, Aloe-emodin, Chrysophanol, Aloe-emodin rhamnoside, Rhabarberon
Curacao Aloes (*C1):
Isobarbaloin
Natal Aloes (*C1):
Homonataloin
Aloe saponaria Haw. (*C1):
Aloesaponarin I, Aloesaponarin II, Laccaic acid D methyl ester, Desoxyerythrolaccin

Chromones
Cape Aloes, Socotrine Aloes, Curacao Aloes (*C1):
Aloesin, 2''-O-p-Coumaroylaloesin, 2''-O-Feruloylaloesin
(*C3,C4,C5):
Aloesin (Aloeresin B), Aloeresin A, Aloesone(2-Acetonyl-7-hydroxy-5-methylchromone), Aloesol, (2'R)-Aloesol, (2'S)-Aloesol, (2'R)-8-C-Glucosylaloesol, (2'S)-8-C-Glucosylaloesol, (2'R)-8-C-Glucosyl-7-O-metylaloesol, (2'S)-8-C-Glucosyl-7-O-metylaloesol, 7-O-Methylaloesin, Aloesin 2",3",4",6"-tetra-O-acetate

αーPyrones
A. arborescens Miller var. natalensis Berger (*C1):
Aloearbonaside

Other aromatic compounds
p-Coumaric acid

Naphthalenes
A. saponaria (*C1):
Aloesaponol I, Aloesaponol II

Chemical structure



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Pharmacological effectBarbaloin:hypercholeresis in small dose,enhanced bowel movement.Barbaloin is C-glycoside of aloe-emodin anthrone. It is metabolized into aloe-emodin anthrone by Eubacterium sp. BAR, enteric bacteria in human intestine. This component stimulates peristalsis and has cathartic effect. (C3,C6).
DNA sequenceAF234338, AJ290255, AJ290289
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseConstipation, Lightheadedness, Red eye, Insomnia, Ear buzzing, Restlessness, Abdominal pain, Malnutrition, Dental caries
Formulation
Related drugsSocotrine Aloes, Curacao Aloes, Natal Aloes, Bombay Aloes (see "Remarks")
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 218-221.
C2)Outline of Pharmacognosy, a Textbook, p334.
C3)Planta Med.,57,15(1991).
C4)Natural Drugs and the Digestive Tract,299(1992).
C5)Chem.Pharm.Bull.,39,704(1991).
C6)Biol.Pharm.Bull.,19,136(1996).
RemarksLuhui has the following species as well as Cape Aloes:
 1) Socotrine Aloes:Aloe perryi Baker (produced in Socotra Island Northeast Africa)
 2) Curacao Aloes:Aloe vera L. and A. vera L. var. chinensis (Haw.) Berger (produced in Curacao Island in Caribbean Barbados)
 3) Natal Aloes:Aloe bainesii Th. Dyer. is common (produced in Natal South Africa, Rhodesia region)
 4) Bombay Aloes:Aloe perryi Baker (produced in East Africa).
Socotrine Aloes and Curacao Aloes are also called Aloe Hepatica. The Aloes which is called "keeping the doctor away" in folklore is Aloe arborescens Miller (produced in South-east Africa, Jap. Name: Kidachiaroe) or its variant, A. arborescens Miller var. natalensis Berg. They are different from the original plant of medicinal Aloes. The fresh liquid of Aloe arborescens Miller is taken orally as a folk medicine for gastrointestinal disease or constipation. It is also applied externally for burns, wounds and scratches.
Last renewal date2022/07/28