Crude drug sample data base
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Crude drug name | Market name | アカメガシワ |
|---|---|---|
| Formal name | アカメガシワ | |
| Japanese name | あかめがしわ, Akamegashiwa | |
| Vernacular name | Akamegashiwa | |
| Latin name | Malloti Cortex (JP) | |
| English name | Mallotus Bark (JP) | |
| Original plant name | Mallotus japonicus Mueller Argoviensis , (Akamegashiwa) | |
| Family name | Euphorbiaceae | |
| Used part | Classification | Plant origin | Sub classification | bark |
| Production area information | Japan, Miyazaki Pref. | |
| Collection information | Japan, Osaka Pref. , Nippon Funmatsu Yakuhin Co., Ltd. | |
| Collection date | 1985/11/16 | |
| Collector | Tsuneo Namba | |
| TMPW No. | 8182 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
31.9110956
131.4238934
Production area information
Japan,Miyazaki Pref.
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png
Scientific information data base
| Common name | アカメガシワ（赤芽柏，将軍木皮）, Akamegashiwa, Malloti Cortex (JP18), Mallotus Bark (JP18) | |||
|---|---|---|---|---|
| crude drug image |
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| Original plant name | Mallotus japonicus Mueller Argoviensis, (Akamegashiwa) | |||
| original plant image |
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| Family name | Euphorbiaceae | |||
| Used part | bark | |||
| Official compendium | JP XVIII | |||
| Clinical application | As an antiulcer drug, Malloti Cortex is applied for gastric ulcer, duodenal ulcer, gastrointestinal disease and cholelithiasis. | |||
| Medical system | Folk medicine | |||
| Chemical constituent | Cardiac glycosides (*C1): [種子/seed] Corotoxigenin, Mallogenin, Coroglaucigenin, Panogeninの3-O-alpha-L-Rhamnopyranosideと3-O-beta-D-Glucopyranosyl-(1→4)-alpha-L-Rhamnopyranoside, Corotoxigenin beta-D-glucopyranosyl-(1→6)-beta-D-glucopyranosyl-(1→4)-alpha-L-rhamnopyranoside Flavones & Flavonols (*C1): [樹皮/bark] Rutin Tannins (*C1): [葉/leaf] Geraniin, Mallotusinic acid, Mallotinic acid Other aromatic derivatives (*C1): [樹皮/bark] Bergenin (*C2,C3): [果皮/pericarp] Butyrylmallotochromene, Isobutyrylmallotochromene, Isomallotochromanol, Isomallotolerin | |||
| Chemical structure |      
※画像をクリックすると、拡大して表示されます。 | |||
| Pharmacological effect | Bile excretion（water extract of bark：suppression，water extract of leaves：stimulation in small doses，suppression at large doses）．Suppression in gastric juices secretion（bergenin）． | |||
| DNA sequence | AJ275677, AJ275678 | |||
| Disease | Gastric ulcer, Duodenal ulcer, Dyskinesia of the colon, Cholelithiasis, Acid indigestion | |||
| Formulation | ||||
| Related drugs | Kamara (see Remarks) | |||
| References | JP18: The 18th edition of the Japanese Pharmacopoeia. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 150-153. C2)J.Nat.Prod.,51,708(1988). C3)Chem.Pharm.Bull.,38,698(1990). | |||
| Remarks | The leaves of Akamegashiwa are applied externally for swelling. The hair and cilia of the fruit of Mallotus philippinensis Muell.-Arg., congener of Akamegashiwa, are called Kamara. It is used as teniacide. | |||
| Last renewal date | 2023/11/30 | |||
