Crude drug sample data base
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Scientific information data base
| Common name | 肉豆蔲, Roudoukou, Myristicae Semen (JP), (CP), Nutmeg (JP), (CP) | |||||
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| Original plant name | Myristica fragrans Houttuyn, (Nikuzuku) | |||||
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| Family name | Myristicaceae | |||||
| Used part | seed (aril and seed coat) | |||||
| Quality for selection | Fresh, high-quality material is characterized by a cross section with a beautiful, vivid reddish marble-like pattern and has a superior aroma and flavor. (TN) | |||||
| Official compendium | JHMC (1989), JP XIX, CP (2025 ed.) | |||||
| Clinical application | It is used as an aromatic stomachic and carminative for the treatment of loss of appetite, abdominal distension, abdominal pain, diarrhea, chronic colitis, and intestinal tuberculosis. It is also used in the production of nutmeg oil and nutmeg butter. | |||||
| Medical system | Traditional Chinese medicine | |||||
| Drug effect in traditional medicine | Traditional classification | Astringents and haemostatics | ||||
| Beneficial effect | [Property and Flavor] Warm; pungent. [Meridian Tropism] Spleen, stomach and large intestine meridians. [Actions] To warm the middle energizer and move qi, astringe the intestines to check diarrhea. [Indications] Spleen-stomach deficiency cold, chronic diarrhea, distending pain in the epigastrium and abdomen, reduced food intake, vomiting. | |||||
| Chemical constituent | Fatty acids (*C1): Myristic acid Lipids (*C1): Oleic acidその他のglyceride, Trimyrisate Monoterpenoids (*C1): d-Camphene, d-alpha-Pinene, Dipentene, d-Borneol, l-Terpineol, Geraniol (*C7): d-Linalool, d-beta-Pinene, dl-Limonene Phenylpropanoids (*C1): Safrole, Myristicin, Acyclic bis-phenylproponoides M. fragrans (*C2,C3,C4,C5,C6): erythro-2-(4"-Allyl-2",6"-dimethoxyphenoxy)-1-(3',4',5'-trimethoxyphenyl)propan-1,3-diol, Fragransol-C, Fragransol-D, Myristicanol-A, Myristicanol-B, 2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propane, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3-hydroxy-4,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2-methoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, threo-2-(4"-Allyl-2"-methoxyphenoxy)-1-(4'-hydroxy-3'-methoxyphenyl)propan-1-ol, trans-2,3-Dihydro-7-methoxy-2-(3,4-methoxyphenyl)-3-methyl-5-(1-(E)-propenyl)benzofuran, 2,3-Dimethyl-1,4-bis-(3,4-methylenedioxyphenyl)butan-1-ol, Fragransin A2 Fragransin B1, Fragransin B2, Fragransin B3, Fragransin C1, Fragransin C2, Fragransin C3a, Fragransin C3b, Fragransin D1, Fragransin D2, Fragransin D3, Fragransin E1, Fragransol-A, Fragransol-B, thero-1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxy-4-(1(E)-propenyl)phenoxy)propan-1-ol, erythro-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol, threo-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol | |||||
| Chemical structure |
※画像をクリックすると、拡大して表示されます。 | |||||
| Pharmacological effect | Low dose: appetizer. High dose: headache, dizziness, lethargy, hallucination. | |||||
| DNA sequence | AF197768, AF206968 | |||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
| Disease | Muddy and watery stool, Proctoptosis, Diarrhea, Abdominal pain, Full stomach, Vomitting | |||||
| Formulation | rarely used in formula | |||||
| References | JP: The 19th edition of the Japanese Pharmacopoeia. CP: Pharmacopoeia of the People's Republic of China 2025 edi. C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 241-242. C2) Phytochemistry,27,563(1988). C3) Chem.Pharm.Bull.,36,648(1988). C4) Chem.Pharm.Bull.,35,668(1987). C5) Chem.Pharm.Bull.,34,3885(1986). C6) Chem.Pharm.Bull.,35,3315(1987). C7) Outline of Pharmacognosy, a Textbook, pp 310-311. | |||||
| Remarks | Related products include Macassar nutmeg and Papua nutmeg (Myristica argentea Warb.), which are produced in Indonesia and New Guinea, and Bombay nutmeg (Myristica malabarica Lam.), which is produced in India. However, both contain lower amounts of essential oil and are therefore considered to be of inferior quality. | |||||
| Last renewal date | 2026/07/07 | |||||










