Crude drug sample data base

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Crude drug name

Market name炉貝
Formal name炉貝
Japanese nameろばい, Robai
Vernacular nameLubei
Latin nameFritillariae Bulbus
English nameFritillary Bulb
Original plant nameFritillaria delavayii> Franch.
Family nameLiliaceae
Used partClassificationPlant origin
Sub classification bulb (corm)
TMPW No.9417

Scientific information data base

Common name川貝母, Chuanbeimu, Fritillariae Cirrhosae Bulbus (CP2020, Tendrilleaf Fritillary Bulb (CP2020)
Synonyms川貝, 松貝, 青貝, 松川貝, 西貝, (炉貝)
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Original plant nameFritillaria cirrhosa D. Don., Fritillaria unibracteata Hsiao et K.C. Hsia, Fritillaria przewalskii Maxim.
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Family nameLiliaceae
Used partbulb
Quality for selectionGood Beimu is small. It has white outside and tannish flesh side. (NI)
Official compendiumCP (2020 ed.)
Clinical applicationAs an antitussive, expectorant and for draining pus, chuanbeimu is applied for troubled fever, laryngitis, dazzling, cough and thirst. Chuanbeimu strongly effects as expectorant, antitussive and moistening the lung. It is applied for cough due to heat in the lung with malaise.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Expectorants
Beneficial effect[Property and Flavor] Mild cold; sweet, bitter.
[Meridian Tropism] Lung and heart meridians.
[Actions] To clear heat, resolve phlegm and suppress cough, remove toxin, dissipate binds and disperse abscesses.
[Indications] Lung heat and dryness cough, dry cough and scanty phlegm, cough caused by yin consumptive disease, blood in phlegm; scrofula, acute mastitis, lung abscess.
Chemical constituentSteroidal alkaloids
F. cirrhosa (*C1,C2):
Verticine (Peimine),Verticinone (Peiminine)
青貝 (*C1):
Chinpeimine
白松貝 (*C1):
Sonpeimine
西貝 (*C1):
Sipeimine
F. delavayi (*C3):
Chuanbeinone
白炉貝 (*C1):
Beilupeimine

Alkaloids
F. cirrhosa (*C1):
Fritimine
岷貝 (*C1):
Minpeimine, Minpeiminine

Chemical structure


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Pharmacological effectHypotensive (peimine).
DNA sequenceAF199454, AF230318
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseCough, Dry cough, Sore throat, Few sputum, Expectoration of sputum, Thirst, Vertigo
FormulationIkeigoshijunto, Ekkiyoeito, Kikyohakusan, Jiinshihoto, Shionsan, Shijunto, Seihaito, Tokibaimokujingan, Tokiyoketsuto, Ninjin-yoei-to, Baimoto, Haiyoto, Byakugokokinto, Yohaito
Related drugsZhebeimu (Zhebei) (Thunberg Fritillary Bulb), Hubeibeimu (Hubei Fritillary Bulb), Pingbeimu (Ussuri Fritillary Bulb), Yibeimu (Sinkiang Fritillary Bulb)
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 71-73.
C2) Outline of Pharmacognosy, a Textbook,p 336.
C3) CA, 54, 22695 (1960).
RemarksThere are many kinds of Beimu. The major kinds are as follows:
- Zhebeimu (浙貝母) or Zhebei (浙貝): Fritillaria thunbergii Miq.
- Hubeibeimu (湖北貝母): F. hupehensis Hsiao et K.C. Hsia
- Chuanbeimu (川貝母) or Chuanbei (川貝): F. cirrhosa D. Don, F. unibracteata Hsiao et K.C.Hsia, F. przewalskii Maxim.
- Lubeimu (炉貝): F. delavayi Franch.
- Yibeimu (伊貝母) or Yibei (伊貝): F. pallidiflora Schrenk, F. walujewii Regel
- Pingbeimu (平貝母) or Pingbei (平貝): F. ussuriensis Maxim.
Each of them is listed in the Pharmacopoeia of the People's Republic of China under the different articles [Lubeimu (炉貝) is included in Chuanbeimu (川貝母)]. Beimu is an expectorant drug and is divided into two groups. One of them consists of Zhebeimu (浙貝母) and Hubeibeimu (湖北貝母). The other consists of Chuanbeimu (川貝母), Lubeimu (炉貝), Yibeimu (伊貝母) and Pingbeimu (平貝母). The former is used in the treatment of cough, scrofula, carbuncle and wound poison. The latter is used for cough caused by deficiency of Yin or heat in the lung.
Japanese Beimu is the bulb of "Amigasayuri (baimo)" which is the same kind as Zhebeimu (浙貝母). It is cultivated in Nara Prefecture and also called "Yamato-baimo". Beimu must not be used with crude drugs of Aconite root. The description of the name Zhebeimu (浙貝母) is found in "Jing-yue-quan-shu"『景岳全書』(1624) in the first place.
Last renewal date2021/09/27