Crude drug sample data base

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Crude drug name

Market name智異羗活
Formal name羌活
Japanese nameきょうかつ, Kyōkatsu
Vernacular nameKanghwal
Latin nameAngelicae Koreanae Radix
Original plant nameOstericum koreanum Kitagawa (= Angelica koreana Maxim.) 1 or Ostericum grosseserratum Kitagawa (= Angelica uchiyamana Y.) 2, (Chosen'oniudo1 or Nioiudo2)
Family nameUmbelliferae
Used partClassificationPlant origin
Sub classification root + rhizome
Production area informationRepublic of Korea
Collection date1968/04/00
TMPW No.950

Scientific information data base

Common name羌活, Qianghuo, Notopterygii Rhizoma (JP18), Notopterygii Rhizoma et Radix (CP2020), Notopterygium (JP18), Incised Notopterygium Rhizome and Root (CP2020)
Synonyms川羌, 西羌, 蚕羌, 頭羌, 竹節羌, 条羌
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Original plant nameNotopterygium incisum Ting ex H. T. Chang or Notopterygium forbesii Boiss. (B1)
original plant image
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Family nameUmbelliferae
Used partrhizome and root
Quality for selectionThe best Qianghuo is Canqiang (Jap. name: Sankyō) which has rhizomes that resemble silkworms in shape. It is produced in Sichuan Province.
Official compendiumJHMC (1989), CP (2020 ed.), JP XVIII
Clinical applicationAs a painkiller, antispasmodic and metabolic promoter, Qianghuo is applied for headache, arthralgia, rheumatism, partial paralysis and general pain.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Diaphoretics with warm property
Beneficial effect[Property and Flavor] Warm; pungent and bitter.
[Meridian Tropism] Bladder and kidney meridians.
[Actions] To release the exterior and dissipate cold, dispel wmd and remove dampness and relieve pain.
[Indications] Common cold caused by wind-cold headache and stiff nape, painful impediment caused by wind-dampness, sore pain in the shoulder and back.
Chemical constituentOther aliphatic and related compounds
(*C1):
Falcarindiol

Steroid saponins & Sapogenins
(*C1):
Pregnenolone

Phenylpropanoids
(*C1):
trans-Ferulic acid

Coumarins
(*C1):
Isoimperatorin, Bergapten, Cnidilin, p-Hydroxyphenethyl anisate, Notopterol, Notoptol, Bergaptol, Nodakenetin, Nodakenin, Decuroside V, Bergamottin, 6'-O-(trans-feruloyl)-Nodakenin, Bergaptol-O-beta-glucopyranoside, Demethylfuropinnarin
N. incisum (*C1):
Angelical
N. forbesii (*C2):
Bergaptol-O-beta-D-glucopyranoside, 6'-O-trans-Feruloylnodakenin

Stilbenes
(*C1):
4'-Hydroxy-3,5-dimethoxystilbene

Chemical structure






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Pharmacological effectNot exactly known.
DNA sequenceU78412, U78472; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseCommon cold, Chill, Fever, Headache, Swelling and pain of joint, Rheumatism
FormulationKufugedokusan, Seishitsuketanto, Seijokentsuto, Senkyuchachosan, Sokeikakketsuto, Nijutsuto, Kamihassento, Jokinritsuansan, Senkanmeimokuto, Daibofuto, Tokinentsuto, Bunshinkiin, Orenshodokuin, Kijitsudaioto, Kufugedokusan, Kufushokutsuto, Kokikososan, Shin'isan, Jintanto
Related drugsWakyōkatsu (和羌活, Araliae Cordatae Radix), Dokukatsu (独活, Araliae Cordatae Rhizoma)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
B1)Nat.Med.,49,409(1995).
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 89-91.
C2)Chem.Pharm.Bull.,38,2498(1990).
RemarksKenkyōkatsu, produced in Korea, is the root or rhizome of Ostericum koreanum Kitagawa (= Angelica koreana Maxim.) of family Umbelliferae (Jap. name: Chosen'oniudo) or Ostericum grosseserratum Kitagawa (= Angelica uchiyamana Yabe) (Jap. name: Nioiudo).
Both Kenkyōkatsu and Chōkyōkatsu, produced in Japan, are the roots or rhizomes of Angelica pubescens Maxim. (Jap. name: Shishiudo). Recently however, Japanese Qianghuo (Jap. name: Wakyōkatsu) is the slender roots of Aralia cordata Thunb. of family Araliaceae.
Chinese Qianghuo is the root of genus Angelica of family Umbelliferae. Both Qianghuo and Duhuo (Araliae Cordatae Rhizoma) have benefits of expelling wind and removing dampness. They relieves pain and removes palsy as well. Qianghuo is a medicine of Taiyang meridians. It has the advantage of expelling dryness and diaphoresis, and should be used for exterior syndrome due to wind cold, while Duhuo has no effect of diaphoresis. Duhuo is a drug of Yin Minimum Kidney Meridian, and used with Xixin (Asiasari Radix), which has a beneficial effects on headache resulting from Yin Minor Channel. In ancient times, it was said "Qianghuo cures hives and Duhuo cures latent wind. Qianghuo tends to specialize in the exterior and Duhuo tends to specialize in the interior."
Last renewal date2023/03/29