Crude drug sample data base

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Crude drug name

Market name肉豆蔲
Formal name肉豆蔲
Japanese nameにくずく, Nikuzuku
Vernacular nameRoudoukou
Latin nameMyristicae Semen (JP), (CP)
English nameNutmeg (JP), (CP)
Other namesナツメグ
Original plant nameMyristica fragrans Houtt., Nikuzuku, Nutmeg
Family nameMyristicaceae
Used partClassificationPlant origin
Sub classification seed
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date1988/04/00
CollectorTsuneo Namba
TMPW No.9818

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name肉豆蔲, Roudoukou, Myristicae Semen (JP), (CP), Nutmeg (JP), (CP)
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Original plant nameMyristica fragrans Houttuyn, (Nikuzuku)
original plant image
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Family nameMyristicaceae
Used partseed (aril and seed coat)
Quality for selectionFresh, high-quality material is characterized by a cross section with a beautiful, vivid reddish marble-like pattern and has a superior aroma and flavor. (TN)
Official compendiumJHMC (1989), JP XIX, CP (2025 ed.)
Clinical applicationIt is used as an aromatic stomachic and carminative for the treatment of loss of appetite, abdominal distension, abdominal pain, diarrhea, chronic colitis, and intestinal tuberculosis. It is also used in the production of nutmeg oil and nutmeg butter.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Astringents and haemostatics
Beneficial effect[Property and Flavor] Warm; pungent.
[Meridian Tropism] Spleen, stomach and large intestine meridians.
[Actions] To warm the middle energizer and move qi, astringe the intestines to check diarrhea.
[Indications] Spleen-stomach deficiency cold, chronic diarrhea, distending pain in the epigastrium and abdomen, reduced food intake, vomiting.
Chemical constituentFatty acids
(*C1):
Myristic acid

Lipids
(*C1):
Oleic acidその他のglyceride, Trimyrisate

Monoterpenoids
(*C1):
d-Camphene, d-alpha-Pinene, Dipentene, d-Borneol, l-Terpineol, Geraniol
(*C7):
d-Linalool, d-beta-Pinene, dl-Limonene

Phenylpropanoids
(*C1):
Safrole, Myristicin, Acyclic bis-phenylproponoides
M. fragrans (*C2,C3,C4,C5,C6):
erythro-2-(4"-Allyl-2",6"-dimethoxyphenoxy)-1-(3',4',5'-trimethoxyphenyl)propan-1,3-diol, Fragransol-C, Fragransol-D, Myristicanol-A, Myristicanol-B, 2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propane, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3-hydroxy-4,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2-methoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, threo-2-(4"-Allyl-2"-methoxyphenoxy)-1-(4'-hydroxy-3'-methoxyphenyl)propan-1-ol, trans-2,3-Dihydro-7-methoxy-2-(3,4-methoxyphenyl)-3-methyl-5-(1-(E)-propenyl)benzofuran, 2,3-Dimethyl-1,4-bis-(3,4-methylenedioxyphenyl)butan-1-ol, Fragransin A2
Fragransin B1, Fragransin B2, Fragransin B3, Fragransin C1, Fragransin C2, Fragransin C3a, Fragransin C3b, Fragransin D1, Fragransin D2, Fragransin D3, Fragransin E1, Fragransol-A, Fragransol-B, thero-1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxy-4-(1(E)-propenyl)phenoxy)propan-1-ol, erythro-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol, threo-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol

Chemical structure


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Pharmacological effectLow dose: appetizer. High dose: headache, dizziness, lethargy, hallucination.
DNA sequenceAF197768, AF206968
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseaseMuddy and watery stool, Proctoptosis, Diarrhea, Abdominal pain, Full stomach, Vomitting
Formulationrarely used in formula
ReferencesJP: The 19th edition of the Japanese Pharmacopoeia.
CP: Pharmacopoeia of the People's Republic of China 2025 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 241-242.
C2) Phytochemistry,27,563(1988).
C3) Chem.Pharm.Bull.,36,648(1988).
C4) Chem.Pharm.Bull.,35,668(1987).
C5) Chem.Pharm.Bull.,34,3885(1986).
C6) Chem.Pharm.Bull.,35,3315(1987).
C7) Outline of Pharmacognosy, a Textbook, pp 310-311.
RemarksRelated products include Macassar nutmeg and Papua nutmeg (Myristica argentea Warb.), which are produced in Indonesia and New Guinea, and Bombay nutmeg (Myristica malabarica Lam.), which is produced in India. However, both contain lower amounts of essential oil and are therefore considered to be of inferior quality.
Last renewal date2026/07/07
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