Crude drug sample data base

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Crude drug name

Market nameハッカ
Formal name薄荷
Japanese nameはっか, Hakka
Vernacular nameHakka
Latin nameMenthae Herba (JP), Menthae Haplocalycis Herba (CP)
English nameMentha Herb (JP), Peppermint (CP)
Original plant nameMentha arvensis L. var piperascens Malinv., (Hakka)
Family nameLabiatae
Used partClassificationPlant origin
Sub classification aerial part
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date1988/09/22
TMPW No.9844

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base

Common name薄荷, Bohe, Menthae Herba (JP18), Menthae Haplocalycis Herba (CP2020), Mentha Herb (JP18), Peppermint (CP2020)
Synonyms蘇薄荷 (Subohe)
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Original plant nameMentha arvensis Linn. var. piperascens Malinvaud1, Mentha haplocalyx Briquet2, (JP products: Hakka1, CN products: Kōnminto2)
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Family nameLabiatae
Used partterrestrial part
Quality for selectionThe leaf of good Bohe is dark-green and has a strong odor. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an aromatic stomachic and carminative, Bohe is applied for headache, dizziness, sore throat, scrofula and a discomfort feeling of distension in the chest and abdomen. Mostly, it is used as raw material for l-menthol (antiseptic, local anesthesia), peppermint oil and peppermint water.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Diaphoretics with cold property
Beneficial effect[Property and Flavor] Cool; pungent.
[Meridian Tropism] Lung and liver meridians.
[Actions] To disperse wind-heat, clear and sooth head and eyes, soothe the throat, promote eruption, soothe the liver to move qi.
[Indications] Common cold caused by wind-heat, early onset of wind-warmth disease, headache, red eyes, throat impediment, mouth sore, rubella, measles, distention and oppression in the chest and the hypochondriurn.
Chemical constituentMonoterpenoids
(*C1):
l-Menthol(精油約1%の70~90%), l-Menthone, 1,8-Cineole, Isomenthone, d-Neomenthol, alpha-Pinene, Camphene, Menthenone, l-Limonene, Piperitone, Piperitenone, Pulegone

Sesquiterpenoids
(*C1):
beta-Caryophyllene, Germacrene-D

Chemical structure

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Pharmacological effectCentral inhibition, vasodilation, skin stimulation, spasmolysis (essential oil), local stimulation, local anesthesia, spasmolysis, carminative, cholagogue, and anthelmin (menthol).
DNA sequenceZ37420, U28876; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseFever, Chill, Headache, Anhidrosis, Swelling and pain of the throat, Red eye, Measles, Itching, Pain due to flatulence of hypochondrium, Full stomach, Abdominal pain, Vomitting, Diarrhea
FormulationKagenryokakusan, Kagenryokakusan'ippo, Kamishoyosan, Kamishoyosangoshimotsuto, Kyoseihatekigan, Keigairengyoto, Kokyuto, Saikoseikansan, Jiinshihoto, Shaito, Shoyosan, Seiishakato, Seiinrikakuto, Seijobofuto, Seiryoin, Senkanmeimokuto, Senkyuchachosan, Chimobukuryoto, Naisoorento, Hachimishoyosan, Bofutsushosan, Ryutan-shakan-to, Ryokakusan
Related drugsSōiyōhakkayō (Peppermint leaf), Midorihakkayō (Spearmint leaf)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 42-43.
Remarks- Mentha piperita L. (Jap. name: Seiyōhakka) is a natural hybrid between Mentha spicata L. (Jap. name: Midorihakka) and Mentha aquatica L. (Watermint). It is cultivated for gardening and commercial use all over the world. It is a major European crude drug and called Menthae Piperitae Folium (Jap. name: Seiyohakkayō) or Peppermint. Being antispasmodic, carminative and cholagogue, it is used to treat gastrointestinal colic pain, flatulence and chronic gallbladder disease. The essential oil (peppermint oil: 0.5-4%) contains less menthol than that of Chinese Mentha Herb, "Bohe" (Jap. name: Hakka), but has a stronger odor and taste. Peppermint leaf contains menthofuran, however, "Bohe" contains only traces of it. These two can be distinguished by this component.
- The leaf of M. spicata (Jap. name: Midorihakkayō) is the medicine for stomachic and carminative. The essential oil (spearmint oil: 0.8-2.5%) is, as well as peppermint oil, widely used for mouth wash and various sweets. The essential oil contains 50% of carvone and no menthol.
- It is said that the usage of Peppermint leaves in Europe was introduced to China and the eastward, and Japanese Mentha Herb, "Hakka" was utilized. In Japan, "Hakka" is widely cultivated in Hokkaido in order to extract mentha oil (Oleum Menthae Japonicae).
Last renewal date2022/10/28