Crude drug sample data base

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Crude drug name

Market nameNirmasi
Formal nameVatsanabha
Other names   

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Mohri (H)
English nameIndian Napellus
Original plant nameAconitum chasmanthum Stapf ex Holmes, Indian Napellus
Family nameRanunculaceae
Used partClassificationPlant origin
Sub classification root
Collection informationKingdom of Nepal, Kathmandu, Kilagal tole M.G.M. Shakya
Collection date1991/04/13
CollectorTsuneo Namba, et al.
TMPW No.14799

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
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27.7172453
85.3239605
Collection information
Kingdom of Nepal,Kathmandu
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Scientific information data base

Crude drug nameAyurvedic name or
Sanskrit name, English name
Vatsanabha (A. chasmanthum), Indian Napellus
SynonymsAmrta, Vajraranga, Vatsanagaka, Visa, Sthavaravisa.
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Original plant nameAconitum chasmanthum Stapf ex Holmes
Family nameRanunculaceae
Used partRoots
Distribution areaAn erect, perennial herb found in the sub-alpine and alpine western Himalayas between altitudes of 2100m and 3600 m; also found in the mountains of Assam and in the sub-alpine grasslands of Himachal Pradesh.
Common usesVatsanabha is a virulent poison but when mitigated, it works as alternative antiinflammatory, diaphoretic, expectorant, stomachic and nervine tonic. It is employed in large number of drug formulations prescribed for the cure of asthma, diabetes, loss of appetite, paralysis, rheumatic arthritis, typhoid and nasal catarrah.
Chemical constituentAlkaloids
14-O-Benzoyl-8-methoxybikhaconine[(1alpha,6alpha,14alpha,16beta)-20-ethyl-13-hydroxy-1,6,8,16-tetramethoxy-4-methoxymethylaconitan-14-yl benzoate] (*C1), 14-O-Benzoyl-8-ethoxybikhaconine [(1alpha,6alpha,14alpha,16beta)-8-ethoxy-20-ethyl-13-hydroxy-1,6,16-trimethoxy-4-methoxymethylaconitan-14-yl benzoate] (*C1), Chasmanthinine (*C2), Indaconitine hemiactonitrile solvate (*C3)

Others
The alkaloid content of the roots ranges from 2.98 to 3.11 per cent. The following alkaloids have been isolated: indaconitine, chasmaconitine, chasmanthinine, chasmanine and homochasmanine.

Medical systemAyurveda (Traditional Indian medicine)
FormulationMrtunjaya rasa, Hingulesvara rasa, Agnitundi vati, Sanjivani vati, Kaphaketu, Ananda bhairava, Jvaramurari, Tribhuvan kirti rasa and Laghu visa garva taila.
Related drugsThis species is very similar to A. napellus, for which it has often been mistaken. A. chasmanthum has the same uses as A. napellus (= A. ferox).
CommentsIn some books, this species is also considered as Vatsanabha.
ReferencesReference book 

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Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi
p 112.

Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore
3.

Research paper*C1 Parvez, M., Gul, W. and Anwar, S.; Acta Crystallogr., Sect. C: Cryst. Struct. Commun., C54, 790-92 (1998).
*C2 Parvez, M., Gul, W., Anwar, S., Miana, G. A., Atra-Ur-Rahman and Choudhry, M. I.; Acta Crystallogr., Sect. C: Cryst. Struct. Commun., C55, 70-72 (1999).
RemarksOf the Acontinum spp. occurring in India, the roots of nine species are commonly found in the Indian markets. Chemical analysis of the market samples, obtained from various places, has shown that the aconite sold in Indian markets (commonly referred to as Acontinum ferox) is not a single species, but a mixture of three or four species with their alkaloid contents varying from 0.63 to 4.7 per cent. The material coming from Nepal consists of root of A. falconeri Stapf or a mixture of A. falconeri, A. laciniatum Stapf and A. ferox Wall. and A. spicatum Stapf.
Last renewal date2024/04/09