Crude drug sample data base

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Crude drug name

Market nameAttana roots and fruits
Formal nameDhattura
Other names　　　

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Ela-attana, Kalu-attana (Sin)
English nameThorn Apple
Original plant nameDatura metel L. (= Datura fruticosa Linn.), Thorn Apple
Family nameSolanaceae
Used partClassificationPlant origin
Sub classification root
Collection informationDemocratic Socialist Republic of Sri Lanka, Colombo, Ayurveda Cooperation
Collection date1983/02/
TMPW No.1530

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
6.9270786
79.86124300000006
Collection information
Democratic Socialist Republic of Sri Lanka,Colombo
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Crude drug nameAyurvedic name or
Sanskrit name, English name		Dhattura (Root), Thorn Apple
crude drug image
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Original plant nameDatura metel L. (= Datura fruticosa Linn.)
Family nameSolanaceae
Used partRoot, Seeds
Distribution areaA native of tropical Asia and now pantropic in distribution. It occurs in India, Ceylon, China, Philippine islands and in the tropics generally. It is a common weed in waste and cultivated land in Ceylon.
Common usesThe plant is bitter, astringent, germicidal, antiseptic, narcotic, sedative, anodyne and antispasmodic. Powered root is rubbed on the gums for toothache. It is also used for curing rabid dog bites and insanity. Internally, it is given as a remedy for preventing hydrophobia. In Indian traditional medicine, Dhattura is a reputed drug in the treatment of rabies dog bites and poisonous insect bites. The drug improves digestion, cures skin diseases such as itching, scabies, ulcers and leprosy, dandruff, fever, dysuria, piles and inflammatory swellings. It is also useful in respiratory ailments, anaemia, earache, eye diseases, insanity, rheumatism and elephantiasis. In Tanganyika, seed and roots are used as intoxicants. Dried root is smoked by the Swahili tribes for tuberculosis.
Chemical constituentDiterpenoids
From stem bark:
Dauturabietatriene (*C6)

Sterols
From stem bark:
Daturasterol (*C6), beta-Sitosterol (*C6)

From leaves:
Physalindicanol A (*C19)

Withanolides
From leaves:
Daturametelin C (*C1), Daturametelin D (*C1), Daturametelin E (*C1), Daturametelin F (*C1), Daturametelin G-Ac (*C1), Daturilin (*C2), Secowithametelin (*C3), Daturametelin A (*C4), Daturametelin B (*C4, *C19), Withametelin C (*C5), Withametelin D (*C5), Withametelin E (*C5), Datumelin (*C7), Datumetelin (*C8, *C9), Daturilinol (*C10), Withafastuosin D (*C11, *C15), Withametelin H (*C12), Withafastuosin C (*C12), Withafastuosin A (*C13), Withafastuosin B (*C13), Withametelin F (*C14), Withametelin G (*C14), Withafastuosin E (*C15), Withametelin (*C18, *C19, *C20), 12-Deoxywithastramonolide (*C19), Withametelin B (*C19)

From Flowers:
Withafastuosin E (*C17), Withafastuosin F (*C17),Withametelin (*C17), Withametelin B (*C17), Withatatulin B (*C17), Withatatulin D (*C17)

Tropane alkaloids
From steb bark:
Atropine (*C6)

Other nitrogen containing compounds
From Leaves:
(4E,8Z)-1-O-(beta-D-glucopyranosyl)-N-(2’-hydroxyhexadecanoyl)-sphinga-4,8-diene (*C16)

Medical systemAyurveda (Traditional Indian medicine)
ReferencesReference book　

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[2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras)
Vol. 2 (Repr.1997), p 305.

Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi
p 132.

Medicinal plants (Indigenous and exotic) used in Ceylon, Vols. 1-5, 1982. Jayaweera, D.M.A., The National Science Council of Sri Lanka, Colombo
Vol. 5, p 85.

Research paper*C1 Shingu, K., Furusawa, Y. and Nohara, T.; Chem. Pharm. Bull., 37, 2132-35 (1989).
*C2 Siddqui, S., Sultana, N., Ahmad, S. S. and Haider, S. I.; Phytochemistry, 26, 2641-43 (1987).
*C3 Kundu, S., Sinha, S. C., Bagchi, A. and Ray, A. B.; Phytochemistry, 28, 1769-70 (1989).
*C4 Kazushi, S., Tetsuya, K., Yoriko, F. and Toshihiro, N.; Chem. Pharm. Bull., 35, 4359-61 (1987).
*C5 Gupta, M., Manickam, M., Sinha, S. C., Bagchi, A. S. and Ray, A. B.; Phytochemistry, 31, 2423-25 (1992).
*C6 Ali, M. and Shuaib, M.; Indian J. Pharm. Sci., 58, 243-45 (1996).
*C7 Siddiqui, S., Ahmad, S. S. and Mahmood, T.; Pak. J. Sci. Ind. Res., 30, 567-68 (1987).
*C8 Mahmood, T., Ahmad, S. S. and Fazal, A.; Planta Med., 54, 468-69 (1988).
*C9 Mahmood, T., Ahmad, S. S. and Fazal, A.; J. Indian Chem. Soc., 65, 526-27 (1988).
*C10 Mahmood, T., Ahmad, S. S. and Siddiqui, S.; Heterocycles, 27, 101-3 (1988).
*C11 Manickam, M., Padma, P., Chansouria, J. P. N. and Ray, A. B.; Phytother. Res., 11, 384-85 (1997).
*C12 Manickam, M., Kumar, S., Bagchi, A. S., Sinha, S. C. and Ray, A. B.; J. Indian Chem. Soc., 71, 393-99 (1994).
*C13 Manickam, M., Bagchi, A. S., Sinha, S. C., Gupta, M. and Ray, A. B.; Phytochemistry, 34, 868-70 (1993).
*C14 Jarromi, M. A. F., Manickam, M., Gupta, M., Oshima, Y., Yoshiteru, H. S. and Ray, A. B.; J. Cehm. Res., Synop., (6), 234-35 (1993).
*C15 Manickam, M., Awasthi, S. B., Oshima, Y., Hisamichi, K., Takeshita, M., Sahai, M. and Ray, A. B.; J. Chem. Res., Synop., (8), 306-7 (1994).
*C16 Sahai, M., Manickam, M., Gupta, M., Srivastava, A. and Ray, A. B.; J. Indian Chem. Soc., 76, 95-97 (1999).
*C17 Manickam, M., Srivastava, A. and Ray, A. B.; Phytochemistry, 47, 1427-29 (1998).
*C18 Oshima, Y., Bagchi, A., Hikino, H., Sinha, S. C., Sahai, M., Ray, A. B.; Tetrahedron, 28, 2025-28 (1987).
*C19 Gupta, M., Bagchi, A. and Ray, A. B.; J. Nat. Prod., 54, 599-602 (1991).
*C20 Singh, U. P., Prakash, O. and Ray, A. B.; Mycobiology, 29, 96-99 (2001).
Last renewal date2023/11/15
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