Crude drug sample data base

※Click on the image to enlarge it.
Crude drug name

Market nameBiji klabet
English nameFenugreek
Original plant nameTrigonella foenum-graecum Linn., Fenugreek
Family nameLeguminosae
Used partClassificationPlant origin
Sub classification seed
Collection informationRepublic of Indonesia, Akar sari
Collection date1980/01/16
CollectorTsuneo Namba, et al.
IdentifierMangestuti Agil
TMPW No.6727

Scientific information data base

Crude drug nameIndonesian name,
English name
Klabet, Fenugreek
crude drug image
※Click on the image to enlarge it.
Original plant nameTrigonella foenum-graecum Linn.
Family nameLeguminosae
Used partSeeds, leaves
Distribution areaIndigenous to the Medditerranean, it was once cultivated in Java Island [201].
DescriptionAn erect annual herb, 30-60 cm.
Fruits contain 10-20 seeds.
Seeds are brownish-yellow of rhombic shape about 3 mm, deep furrow dividing them into 2 unequal lobes. Taste bitter and peculiar.
Frequency in useModerate
Common usesIt is used as a spice in cooking goat meat. Also to treat cold in horses [201].
Pharmacological effectA study on the chemopreventive activities of Trigonella foenum-graecum Linn. against breast cancer showed that fenugreek seed's extract significantly inhibited the dimethylbenz anthracene -induced mammary hyperplasia and decreased its incidence [PMID:15936223].

On a research to study the effect of soluble dietary fiber fraction of Trigonella foenum-graecum Linn. on glycemic, insulinemic, lipidemic and platelet aggregation status of Type 2 diabetic model rat showed that the plant has a beneficial effect on dyslipidemia and has a tendency to inhibit platelet aggregation in Type 2 model diabetic rats [PMID:12902054].

Evaluation on the preventive efficacy of dietary fenugreek seeds and its major steroidal saponin constituents, diosgenin, on azoxymethane-induced rat colon carcinogenesis during initiation and promotion stages showed that diosgenin inhibits cell growth and induces apoptosis in the HT-29 human colon cancer cell line in a dose-dependent manner [PMID:15298963].
Medical systemIndonesian medicine (Jamu)
Traditional usageTreatment of asthma, cough, irregular menstruation, appetite stimulant, sore throat, digestive problems, haemorrhoids/hemorrhoids, abscesses, fallen hair and rheumatism.
It is also used as a liniment and hair oil, poultice is used to reduce pain [201].
Seeds are used as carminative, tonic, aphrodisiac, cosmetic, and to treat smallpox. Leaves are for treating swellings, injury to the skin caused by heat, as a hair tonic [222].
Formulation1) Hair growth:
 5 grams of powdered seeds of T. foenum-graecum is boiled in 100 ml of oil of Aleurites moluccana, let it stand overnight and use as a hair oil [231].
ReferencesReference book 

Tips!

[201] K. Heyne, Tumbuhan Berguna Indonesia, Vols. 1-4, 1987. Diedarkan Oleh Koperasi Karyawan Departemen Kehutanan, Jakarta, Indonesia.
Vol. 2, p 956.

[203] Departemen Kesehatan Republik Indonesia, Materia Medika Indonesia, Vol. 1 (1977), Vol. 2 (1978), Vol. 3 (1979). Vol. 4 (1980), Vol. 5 (1989), Vol. 6 (1995), Jakarta, Indonesia.
Vol. 3, p 123.

[222] P.T. Eisai Indonesia: Medical Herb Index in Indonesia (Second edition).1995.
p 131.

[231] Soedibyo, Mooryati: Alam Sumber Kesehatan: Manfaat dan Kegunaan (Natural resources for health. Benefits and uses). Balai Pustaka. 1998.
pp 222-223.

Research paper1. Amin A, Alkaabi A, Al-Falasi S, Daoud SA. Chemopreventive activities of Trigonella foenum-graecum (fenugreek) against breast cancer. Cell Biol. Int., 29(8):687-94, 2005. (PMID: 15936223)

2. Raju J, Patlolla JM, Swamy MV, Rao CV. Diosgenin, a steroid saponin of Trigonella foenum-graecum (fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells. Cancer Epidemiol Biomarkers Prev., 13(8):1392-8, 2004. (PMID: 15298963)

3. Hannan JM, Rokeya B, Faruque O, Nahar N, Mosihuzzaman M, Azad Khan AK, Ali L. Effect of soluble dietary fibre fraction of Trigonella foenum-graecum on glycemic, insulinemic, lipidemic and platelet aggregation status of Type 2 diabetic model rats. J Ethnopharmacol., 88(1):73-7, 2003. (PMID: 12902054)
Last renewal date2024/03/08