Crude drug sample data base

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Crude drug name

Market nameDaun urang-aring
Other namesJava: goman, urang-aring (Javanese), te-lenteyan (Madurese); Mollucas: daun tinta (Banda)
Original plant nameEclipta alba Hassk.
Family nameCompositae
Used partClassificationPlant origin
Sub classification leaf
Collection informationRepublic of Indonesia, Akar sari
Collection date1980/01/16
CollectorTsuneo Namba, et al.
IdentifierMangestuti Agil
TMPW No.10456

Scientific information data base

Crude drug nameIndonesian name,
English name		Daun urang-aring
crude drug image
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Original plant nameEclipta alba Hassk.
Family nameCompositae
Used partLeaves
Distribution areaIt occurs worldwide in the tropics and subtropics. It occurs elsewhere in Java from lowland to 1500m altitude. It grows as a weed in rice fields, sugar and coconut plantations, scattered in grassy plains [222].
DescriptionLeaves opposite, simple, oblong-lanceolate, 2-7 cm x 1-2 cm, base attenuate, apex pointed, margins entire or slightly toothed.
The plant is a straggling annual or rather short-lived perennial herb, stem cylindrical, rooting at the lower node, reddish, with tap root. Inflorescence axillary or terminal head, solitary or up to 3 together, flowers white. Fruit an oblong achene, triangular or compressed with 1 central rib on each side, black [220].
Drug effectSweet, sour, cooling [231].
Specific actionsHemostatic, antipyretic [231].
Frequency in useModerate
Common usesLeaves are crushed in water to obtain juice which is commonly used to cool the head, rinse hair to stimulate hair growth and to keep the hair black. A mixture with coconut oil is used to stimulate hair growth. It is also rubbed all over the scalp of a newborn baby to stimulate hair growth.
Cooked leaves are eaten [201].
Pharmacological effectThe active constituent wedelolactone is a potent and selective 5-lipoxygenase-inhibitor through an oxygen radical scavenger mechanism [220].

Fraction of alcoholic extract of fresh leaves of Eclipta alba contains coumestan wedelolactone and desmethylwedelolactone as major components and exhibited maximum hepatoprotective activity [PMID:11883149].

Aqueous and hydroalcoholic extracts of Eclipta alba showed a potential neuropharmacological activity as a nootropic and having the property of attenuating stress induced alterations [PMID:16054316].

Leaf suspension of E. alba could reduce blood glucose level, which shows that it possesses an anti hyperglycemic activity [PMID:15369623].
Medical systemIndonesian medicine (Jamu)
Traditional usageThe leaves are used to treat difficulty in breathing, headache, boils, toothache, menstrual disorder [201].
Juice of the leaves is rubbed on the chest to treat breathing difficulties. Crushed leaves is mixed with a small amount of salt and rubbed on the scalp to treat headache [201].
Formulation1) Hair loss:
 10 grams of leaves is pounded and add 1/2 cup of water, squeezed and strained. Apply the juice on the scalp with light massage [207].
A mixture of crushed leaves with coconut oil is used as a hair oil [201].

2) Haemorrhoids/hemorrhoids:
 7 aboveground parts of E. alba, 7 roots of Euphorbia prostata, 7 pieces of leaves of Coleus scutellaroides, 1 piece of Helicteres isora, are boiled with 110 ml of water. Drink 100 ml of the decoction once a day for 14 days [231].
ReferencesReference book　

Tips！

[201] K. Heyne, Tumbuhan Berguna Indonesia, Vols. 1-4, 1987. Diedarkan Oleh Koperasi Karyawan Departemen Kehutanan, Jakarta, Indonesia.
Vol. 3, p 1833.

[207] Badan Penelitian Dan Pengembangan Kesehatan and Departemen Kesehatan, Kesejahteraan Sosial Ri. Vols. 1-5, Inventaris Tanaman Obat Indonesia, Jakarta, Indonesia.
Vol. 1, Part 1 (2000), pp 99-100.

[220] van Valkenburg, J.L.C.H. and Bunyapraphatsara, N. (editors). Plant Resources of South-East Asia No. 12 (2). Medicinal and posionous plants 2. Prosea Foundation, Bogor, Indonesia, 2002.
pp 237-240.

[222] P.T. Eisai Indonesia: Medical Herb Index in Indonesia (Second edition).1995.
p 222.

[228] Christophe, Wiart.: Medicinal Plants of Southeast Asia. Prentice Hall. Malaysia. 2002.
pp 311-312.

[231] Soedibyo, Mooryati: Alam Sumber Kesehatan: Manfaat dan Kegunaan (Natural resources for health. Benefits and uses). Balai Pustaka. 1998.
pp 380-381.

Research paper1. Thakur VD, Mengi SA. Neuropharmacological profile of Eclipta alba (Linn.) Hassk. J Ethnopharmacol. 31;102(1):23-31., 2005. (PMID: 16054316)

2. Ananthi J, Prakasam A, Pugalendi KV. Antihyperglycemic activity of Eclipta alba leaf on alloxan-induced diabetic rats. Yale J Biol Med. 76(3):97-102, 2003. (PMID: 15369623)

3. Singh B, Saxena AK, Chandan BK, Agarwal SG, Anand KK. In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Indian J Physiol Pharmacol. 45(4):435-41, 2001. (PMID: 11883149)
RemarksThe 5-lipoxygenase inhibition, hepatoprotective, antimyotoxic, anti-haemorrhoagic/anti-hemorrhoagic effects of the extracts and its constituents need further researches [220].
Last renewal date2024/03/05
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