Crude drug sample data base
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Crude drug name | Market name | Sadikka |
|---|---|---|
| Formal name | Jatipatri | |
Other names Tips！ | Aril - Japattari, Javitri (T), Jotri, Japatri, Jayaoatri (B), Javatari, Japatri, Jotri, Jayaoatri (H), Japatri, Jadipattiri (K), Jatipatri, Jadipattiri (M), Jatipatri, Jadipattiri (Te), Jatipatri, Japatri, Jadipattiri (Ta) & Kernel - Jaiphal (T), Jayaphal (B), Jaiphal (H), Jajikayi, Jajikai, Jadikai (K), Jatikka, Jajikai, Jadikai (M), Jajikaya, Jajikai, Jadikai (Te), Jatikkay, Jajikai, Jadikai (Ta), Dzatiphala (Ti), Jaiphatri, Jayaphal (N), Sadikka, Wasawasi (Sin) | |
| English name | Nutmeg | |
| Original plant name | Myristica fragrans Houtt., Nutmeg | |
| Family name | Myristicaceae | |
| Used part | Classification | Plant origin | Sub classification | seed |
| Production area information | Democratic Socialist Republic of Sri Lanka | |
| Collection information | Democratic Socialist Republic of Sri Lanka, Colombo , W. Wilbert & Co. | |
| Collection date | 1980/02/08 | |
| Collector | Tsuneo Namba, et al. | |
| TMPW No. | 6222 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
Production area information
Democratic Socialist Republic of Sri Lanka
https://ethmed.toyama-wakan.net/img/pin_san.png
6.9270786
79.86124300000006
Collection information
Democratic Socialist Republic of Sri Lanka,Colombo
https://ethmed.toyama-wakan.net/img/pin_nyu.png
Scientific information data base
| Crude drug name | Ayurvedic name or Sanskrit name, English name | Jatipatri (Seed), Nutmeg | |||
|---|---|---|---|---|---|
| crude drug image |
| ||||
| Original plant name | Myristica fragrans Houtt. | ||||
| Family name | Myristicaceae | ||||
| Used part | Fruit (Seed, Kernel, Aril) | ||||
| Distribution area | A native of E. Moluccas and other Indian Islands, Amboya, Borneo, New Guinea etc. It is now cultivated in Ceylon, Malaya, Philippines, W. Indies and South America. | ||||
| Common uses | Nutmeg is aromatic, aphrodisiac, antiinflammatory, anthelmintic, digestive, carminative, stomachic, expectorant, diuretic, antispasmodic, stimulant, ophthalmic, anticonvulsant, antiseptic, constipating and tonic. It is useful in inflammations, dyspepsia, flatulence, colic, cough, asthma, catarrh, diarrhoea/diarrhea, vomiting, strangury, amenorrhoea/amenorrhea, dysmenorrhoea/dysmenorrhea, ulcers, skin diseases, insomnia and fever. Nutmeg butter is used as a mild external stimulant in ointments, hair lotions and plasters and forms a useful application in cases of rheumatism, paralysis and sprains. Seeds of this tree are mainly used as a flavouring agent for medical and culinary purposes. | ||||
| Pharmacological effect | Excessive dose of nutmeg has a narcotic effect, symptoms of epileptic convulsions and delirium appear after 1-6 hours. The oil of nutmeg is mildly counterirritant. It is some-what toxic owing to the presence of myristicin and should be used with caution. Alcoholic extracts of nutmeg show antibacterial activity against Micrococcus pyogenes var aureus. An aqueous extract on nutmeg is reported to show antisecretory activity against E. coli, LT, the heat labile enterotoxin. The hexane soluble fraction of the alcoholic extract inhibited the LT and ST (heat stable) enterotoxin and induced secretory response in rabbit or guinea pig. An Ayurvedic composite drug preparation containing nutmeg as one of the ingredients was found to give 45% improvement in patients showing generalized weakness, on account of its adaptogenic, growth enhancing and health promoting properties. Some of the drugs containing nutmeg are reported to exhibit hallucinogenic properties, causing brain damage at higher doses and even paralysis. Detailed studies have shown that nutmeg is a minor hallucinogenic plant, that most of the volitional control is a minor hallucinogenic plant, that most of the drug is short. The after effects, if any, are very mild. Nutmeg also showed strong mutagenic activity with an LC 50 of 268?g/ml on shrimps. The hexane extract from nutmeg was found to significantly inhibit hepatic drug metabolizing enzyme activity due to the presence of the active principles. Myristicin and licarrin-B were found to possess CNS depressant properties too. Nutmeg and mace constitute the herbal drug 'Prajana' possessing neurological activity. The drug reduces spontaneous locomotion activity. It potentiated phenobarbitone sleeping time. In all, it exerted only a moderate degree of CNS depression. Mice treated with extracts of nutmeg or with myristicin developed covaling liver DNA adducts. These adducts were also detected in foetal liver when pregnant mice were incubated with myristicin. The possible implications of such a development to human health is being studied. Nutmeg oil showed 70% anti-implantation activity at 40mg/ kg orally in rats. It showed strong nematicidal activity against Meloidogyne incognita. The oil also showed weak insecticidal activity. | ||||
| Medical system | Ayurveda (Traditional Indian medicine) | ||||
| References | Reference book Tips！ | [2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras) Vol. 4 (Repr.1997), p 90. Medicinal plants (Indigenous and exotic) used in Ceylon, Vols. 1-5, 1982. Jayaweera, D.M.A., The National Science Council of Sri Lanka, Colombo Vol. 4, p 109. | |||
| Last renewal date | 2023/11/22 | ||||
