Crude drug sample data base

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Crude drug name

Market nameDaim Jamb (Psidium guajava) (Daun jambu)
Other namesJava: jambu klutuk, petokal, tokal (Javanese), jhambhu bhender, jhambhu bighi (Madurese), Sumatera: glima breueh (Aceh); Celebes: wayamas, jambu paratugala (Makasar); Mollucas: gawaya (north Halmahera), gawaya (Ternate) [201]
English nameGuajava
Original plant namePsidium guajava Linn., Guajava
Family nameMyrtaceae
Used partClassificationPlant origin
Sub classification leaf
Collection informationRepublic of Indonesia, National Institute of Health Res.& Dev.
Collection date1994/02/26
CollectorKatsuko Komatsu, et al.
IdentifierMangestuti Agil
TMPW No.14137

Scientific information data base

Crude drug nameIndonesian name,
English name		Daun jambu biji, Guajava
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Original plant namePsidium guajava Linn.
Family nameMyrtaceae
Used partLeaves, fruits, roots, stem bark
Distribution areaIn Java it occurs up to 1200 m altitude and sometimes are wild [201].
DescriptionThe fruit has a strong, sweet, musky odor when ripe; round, ovoid, or pear-shaped, 5-10 cm long, with 4 or 5 protruding floral remnants (sepals) at the apex; thin and light-yellow skin, frequently blushed with pink. Next to the skin is a layer of somewhat granular flesh, 3-12.5 mm thick, white, yellowish, light- or dark-pink, or near-red, juicy, acid, subacid, or sweet and flavorful. The central pulp is juicy and normally filled with very hard, yellowish seeds, , though some rare types have soft, chewable seeds.When immature and until a very short time before ripening, the fruit is green, hard, gummy within and very astringent.
The plant is a small tree with spreading branches, the guava is easy to recognize because of its smooth, thin, copper-colored bark that flakes off, showing the greenish layer beneath; The leaves, aromatic when crushed, are evergreen, opposite, short-petioled, oval or oblong-elliptic, leathery, with conspicuous parallel veins, and more or less downy on the underside. Flowers are fragrant, white, borne singly or in small clusters in the leaf axils, with 4 or 5 white petals which are quickly shed.
The fruit has a strong, sweet, musky odor when ripe; round, ovoid, or pear-shaped, 5-10 cm long, with 4 or 5 protruding floral remnants (sepals) at the apex; thin and light-yellow skin, frequently blushed with pink. Next to the skin is a layer of somewhat granular flesh, 3-12.5 mm thick, white, yellowish, light- or dark-pink, or near-red, juicy, acid, subacid, or sweet and flavorful. The central pulp is juicy and normally filled with very hard, yellowish seeds, though some rare types have soft, chewable seeds.When immature and until a very short time before ripening, the fruit is green, hard, gummy within and very astringent.
Drug effectSweet, astringent, neutralize [231].
Specific actionsLeaves are good for dysenteri, irregular menstruation, white vaginal discharge, diarrhea, indigestion in children, inflammation of intestine, fungal infection, skin diseases [231].
Fruits are good for dysentery and diabetes.
Frequency in useModerate.
Common usesYoung and ripe fruits are eaten raw or boiled to make various canned food.
Pounded leaves are used to give black color in pandanus leaves [201].
Pharmacological effectThe hypoglycemic effect of P. guajava leaf aqueous extract was examined in normal and diabetic rats, using streptozotocin (STZ)-induced diabetes mellitus model. Results indicate that the extract the leaf aqueous extract of P. guajava possesses hypoglycemic and hypotensive properties [PMID: 16395418].

Study on the antiinflammatory and analgesic properties of the aqueous leaf extract of Psidium guajava on laboratory animals indicate that the extract of analgesic and anti-inflammatory [PMID: 17003849]].

Extract from Psidium guajava leaves possesses antidiabetic effect in type 2 diabetic mice model and these effect is, at least in part, mediated via the inhibition of protein tyrosine phosphatase1B [PMID: 15619559].
Medical systemIndonesian medicine (Jamu)
Traditional usageDecoction of the roots and leaves is a good remedy for dysentery, gastroenteritis, especially vomiting and heavy diarrhea in children. Roots, stem bark, leaves are used for persistent diarrhea in Java. It works as an astringent .
Steepings of guava and betle leaves in water are good for leucorrheal discharge [201].
It may also cause constipation in the case of consumption of large amounts of guava fruits.
Formulation1) Stomachache and diarrhoea/diarrhea:
 9 pieces of young guava leaves, rhizome of turmeric (size of an adult finger), 4 pieces of seeds of Parkia biglobosa (fry without oil), 4 grams of thallus of Usnea misaminensis (Usnea sp.), are boiled with 110 ml of water. Drink 100 ml of the decoction twice a day in the morning and evening for 4 days [231].

2) Leucorrhoea/leucorrhea:
 2 handful of young guava leaves, 7 pieces of betle leaves are boiled with 200 ml of water. Drink 200 ml of the decoction (upper part of the decoction) twice a day for 7 days [231].
ReferencesReference book　

Tips！

[201] K. Heyne, Tumbuhan Berguna Indonesia, Vols. 1-4, 1987. Diedarkan Oleh Koperasi Karyawan Departemen Kehutanan, Jakarta, Indonesia.
Vol. 3, p 1506.

[207] Badan Penelitian Dan Pengembangan Kesehatan and Departemen Kesehatan, Kesejahteraan Sosial Ri. Vols. 1-5, Inventaris Tanaman Obat Indonesia, Jakarta, Indonesia.
Vol. 1, Part 2 (2001), pp 291-292.

[231] Soedibyo, Mooryati: Alam Sumber Kesehatan: Manfaat dan Kegunaan (Natural resources for health. Benefits and uses). Balai Pustaka. 1998.
pp 160-161.

Research paper1. Ojewole JA. Antiinflammatory and analgesic effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rats and mice. Methods Find Exp Clin Pharmacol. 28(7):441-6, 2006. (PMID: 17003849)

2. Ojewole JA. Hypoglycemic and hypotensive effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract. Methods Find Exp Clin Pharmacol. J Ethnopharmacol. 27(10):689-95, 2005. (PMID: 16395418)

3. Oh WK, Lee CH, Lee MS, Bae EY, Sohn CB, Oh H, Kim BY, Ahn JS. Antidiabetic effects of extracts from Psidium guajava. 15;96(3):411-5, 2005. (PMID: 15619559)

4. Begum S, Hassan SI, Ali SN, Siddiqui BS. Chemical constituents from the leaves of Psidium guajava. Nat Prod Res. 18(2):135-40, 2004. ( PMID: 14984086)
Remarks[DNA sequences] AY781085, AY781086, AY781087, AY781088, AY781089, AY781090, AY781091, AY781092, AY781093, AY781094, AY781095, AY781096, AY781097, AY781098, AY781099
Last renewal date2024/03/01
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