Crude drug sample data base

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Crude drug name

Market nameKunci
Other namesJava: temu kunci (Sundanese), temo konce (Madurese); Sumatra: tamu kunci (Minangkabau); Celebes: temu konci (Makasar), teki kunci (Manado) [201]
English nameChinese keys
Original plant nameBoesenbergia pandurata Schltr., Chinese keys
Family nameZingiberaceae
Used partClassificationPlant origin
Sub classification rhizome
Production area informationRepublic of Indonesia
Collection informationRepublic of Indonesia, Surakarta, Central Java Prov.
Collection date2006/03/04
CollectorOthers
IdentifierMangestuti Agil
TMPW No.24990

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
Republic of Indonesia
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-7.575488699999999
110.82432719999997
Collection information
Republic of Indonesia,Surakarta, Central Java Prov.
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Scientific information data base

Crude drug nameIndonesian name,
English name		Temu kunci, Chinese keys
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Original plant nameBoesenbergia pandurata Schltr.
Family nameZingiberaceae
Used partRhizome
Distribution areaIt is native to Java and Sumatra (Indonesia). It grows wild in the teak forests of Central and East Java [204].
DescriptionThe plant is a perennial herb, 30-80 cm tall, with leafy shoots bearing 3-7 erect leaves and about 3 bladeless, reddish sheaths at the base.
Rhizome at the base of leafy shoots, composed of more or less globose joints, largely fused; yellow-brown outside, bright yellow inside and fragrant when bruised. Roots tuberous and fleshy, color and fragrance like rhizome. Leaves alternate, biseriate, erect, fragrant when bruised; blade elliptical-oblong to broadly lanceolate , dark green, glabrous with several raised, parallel veins and scattered dots above, pale green. Inflorescence terminal on leafy shoot, almost completely hidden by the upper leaf sheath, bearing about 10 flowers. [201, 204].
Drug effectCooling, blood cleansing, carminative, antipyretic, expectorant, anti-rheumatic, good for post-partum muscular pain [204, 231].
Specific actionsTonic, stomachic, carminative [204].
Frequency in useAbundant
Common usesThe plant is cultivated in Indonesia for its rhizome which is used as an aromatic spicy flavouring for food. Throughout Indonesia, the rhizome is used as a spice in cooking. The young spicy shoots are also a substitute for the rhizomes and they are eaten raw in Java. In the Caruban district (East Java), leaves are used together with teak leaves as a wrapper for fermented local soy bean cake called ''tempe'' [204].
Pharmacological effectCardamonine is reported to have anti tumor properties [204].

The cyclohexenyl chalcone derivatives, Hydroxypanduratin A and (-)-panduratin A showed significant topical anti-inflammatory activity in the assay of TPA-induced ear edema in rats [PMID: 11809452].

A new cyclohexenyl chalcone named panduratin C and chalcone derivatices from the methanol extract of B. pandurata have been isolated. In searching for their anti HIV-1 protease inhibitor, it is known that hydroxyl panduratin A and panduratin A are active principles against HIV-1 protease [PMID: 16263298].

Six compounds were isolated from fresh rhizomes of Boesenbergia pandurata Schult as strong antimutagens. It was known that the antimutagenic effect of the compounds was mainly due to the inhibition of the first step of enzymatic activation of heterocyclic amines [PMID: 11410007].

The rhizome of Boesenbergia pandurata Schult. was found to possess potent antioxidant activity in a rat brain homogenate model. Bioassay-guided isolation of the active compounds from a CH2Cl2-MeOH (1:1) extract led to the isolation of 5-hydroxy-7-methoxyflavanone, panduratin A, 5,7-ihydroxyflavanone, 2',6'-dihydroxy-4'-methoxychalcone, 2',4'-dihydroxy-6'-methoxychalcone, and 4-hydroxypanduratin A. Panduratin A, 4-hydroxypanduratin A, and 2',6'-dihydroxy-4'-methoxychalcone were also found to exert neuroprotective effects [PMID: 16960369].
Medical systemIndonesian medicine (Jamu)
Traditional usageSliced rhizomes are chewed together with Areca seeds for curing dry cough and thrush.
Together with fennel seeds and bark of Alyxia reinwardtii, rhizomes are pounded or crushed to make a paste which is taken for curing difficulty in urination in children and swollen abdomen. Together with coconut milk and Sulfur (sulphur), it is used to treat ringworm infestation.
A cultivar of the plant has yellow flowers and the inner part of the rhizome is yellowish-green; the rhizome is used to treat inflammation of the uterine and a mixture with other spice is used to treat vaginal infection [201].
It is used medicinally for indigestion; as a stomachic and carminative. It is used externally to treat rheumatism and post-partum muscular pain [204].
Formulation1) Leucorrhoea/leucorrhea:
  5 rhizomes is boiled with 110 ml of water. Stand to cool and strain. Drink 100 ml of the decoction for 10 days [231].

2) Stomach upset:
 2 fried rhizomes, 7 pieces of coriander fruits, 1 piece of Helicteres isora fruit are mixed with 100 ml of water and boiled. Stand to cool and strain. Drink 100 ml of the decoction once a day for 4 days [231].

3) Swollen uterus:
 3 rhizomes is boiled with 110 ml water, stand to cool and strain. Drink 100 ml of the decoction for 14 days [231].
ReferencesReference book　

Tips！

[201] K. Heyne, Tumbuhan Berguna Indonesia, Vols. 1-4, 1987. Diedarkan Oleh Koperasi Karyawan Departemen Kehutanan, Jakarta, Indonesia.
Vol. 1, p 594.

[204] de Guzman, C.C. and Siemonsma, J.S. (Editors), 1999. Plant Resources of South-East Asia No. 13 Species. Backhuys Publishers, Leiden, Netherlands.
pp 83-85.

[231] Soedibyo, Mooryati: Alam Sumber Kesehatan: Manfaat dan Kegunaan (Natural resources for health. Benefits and uses). Balai Pustaka. 1998.
p 367.

Research paper1. Shindo K, Kato M, Kinoshita A, Kobayashi A, Koike Y. Analysis of antioxidant activities contained in the Boesenbergia pandurata Schult. Rhizome. Biosci Biotechnol Biochem., 70(9):2281-4, 2006. (PMID: 16960369)

2. Cheenpracha S, Karalai C, Ponglimanont C, Subhadhirasakul S, Tewtrakul S. Anti-HIV-1 protease activity of compounds from Boesenbergia pandurata. Bioorg Med Chem., 15;14(6):1710-4, 2006. (PMID: 16263298)

3. Tuchinda P, Reutrakul V, Claeson P, Pongprayoon U, Sematong T, Santisuk T, Taylor WC. Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata. Phytochemistry, 59(2):169-73, 2002. (PMID: 11809452)

4. Trakoontivakorn G, Nakahara K, Shinmoto H, Takenaka M, Onishi-Kameyama M, Ono H, Yoshida M, Nagata T, Tsushida T. Structural analysis of a novel antimutagenic compound, 4-Hydroxypanduratin A, and the antimutagenic activity of flavonoids in a Thai spice, fingerroot (Boesenbergia pandurata Schult.) against mutagenic heterocyclic amines. J Agric Food Chem., 49(6):3046-50, 2001. (PMID: 11410007)
Last renewal date2024/03/18
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