資料館生薬データベース

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生薬名

入手時名称Sara
正式名称Punarnava
別名   

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Punarnavaa mool (T), Gadapurna, Punarnaba (B), Sant, Raktapunarnava jar (H), Sanadika (K), Tavizhama, Talutama (M), Attamamidi (Te), Mukkurattai (Ta), Basarpru-burnam (Ti), Lalgaj pumi, Lal purnamava, Purnava, Sanupte (N), Pitasudu-sarana, Sarana (Sin)
英語名Spreading Hogweed
原植物名Boerhavia diffusa Linn. (= Boerhavia repens Linn.), Spreading Hogweed
原植物科名Nyctaginaceae, オシロイバナ科
薬用部位分類植物性生薬
細分類
入手先情報スリランカ民主社会主義共和国, コロンボ, W. Wilbert & Co.
入手年月日1982/02/01
蒐集者難波恒雄, 他
TMPW No11716

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産地情報
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入手先情報
スリランカ民主社会主義共和国,コロンボ
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学術情報データベース

生薬名一般生薬名 (アーユルヴェーダ名又は
サンスクリット名), 英語名
Punarnava, Spreading Hogweed
異名Vrscira, Dirghadala, Raktavrnta, Jatila, Kathillaka, Sunasika, Ksudravarsabhu, Raktapuspa, Vaisakha, Vikasa, Sinadika, Krura, Raktakanda, Varsaketu, Lohita, Raktapatrika, Vikasvara, Visaghni, Pravrsenya, Sarini, Sonapatra, Sona, Sammilitadruma
生薬画像
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原植物名Boerhavia diffusa Linn. (= Boerhavia repens Linn.)
原植物科名Nyctaginaceae, オシロイバナ科
薬用部位Root
分布地域A weed throughout India in waste places, along roadsides upto 2000m in the Himalayas, also cultivated to some extent in Bengal.
重要度Common.
一般応用Roots possess anticonvulsant, analgesic, diuretic, laxative, stomachic, expectorant and alterative properties. They are useful in asthma, oedema, anaemia/anemia, ascites, anasarca, scanty urine, jaundice, strangury, dropsy and internal inflammations. The drug is also reported to be efficacious in abdominal tumours/tumors and cancer. It is also credited with antibacterial and cardiotonic properties. An Ayurvedic drug is preparaed with this drug is reported to cure hypertension, angina and chloesterolaemia (high cholesterol).
応用疾患Pandu (anaemic/anemic conditions), Sopha (oedema), Anila (rheumatic disorder), Gara (a type of poison), Hrdroga (heart diseases), Kasa (cough), Uraksata (chest injury), Sula (colic), Raktapradara (uterine haemorrhage/hemorrhage), Svayathu (oedema), Arsa (piles), Vrana (wounds), Visa (poison), Udara (ascitic types)
成分情報脂肪酸 Fatty acids
Tricont-24-en-1-oic acid (*C5).

その他の脂肪族関連化合物 Other aliphatic and related compounds
Boerhadiffusene (*C4)

ステロール Sterols
Boerhavisterol (*C4), beta-Sitosterol (*C5), Stigmasterol (*C10), Campesterol (*C10)

ステロイドサポニン及びサポゲニン Steroid saponins & Sapogenins
Boerhavilanostenyl benzoate (*C4), Palmityl glycosyl sitosterol (*C10)

リグニン Lignin
Liriodendrin (*C13), Syringaresinol mono beta-D-glucoside (*C13)

キサントン類 Xanthones
Borhavine (*C2),

フラボンとフラボノール Flavones & Flavonols
Borhavone (*C1)

フェノール系化合物 Phenol derivatives
Boeravinone A (*C3, *C10), Boeravinone B (*C3, *C10), Diffusarotenoid (*C4), Boeravinone C (*C7, *C11), Boeravinone D (*C8), Boeravinone E (*C8), Boeravinone F (*C8), Punarnavoside (*C9, *C12)

アルカロイド Alkaloids
Punernavine (*C6)

薬理作用Pharmacological studies have demonstrated that Punarnava possesses diuretic and antiinflammatory properties, maximum activity being present in samples collected in the rainy season. A combination of these two activities makes punarnava a very useful drug for the treatment of inflammatory renal diseases and the common clinical problems like nephrotic syndrome. It is particularly useful as a maintenance drug. It is effective in cases of oedema and ascites resulting from early cirrhosis of the liver and chronic peritonitis. Hypoxanthine-9-L-arabinofuranoside present in the drug was found to lower serum uric acid levels in experimental animals as also in humans. It also produced depressor and negative chronotropic effects in experimental animals. Punarnavoside shows significant antifibrinolytic activity. The drug proved useful as a haematinic and growth promoter in children fed with milk fortified with it.
An ethanolic extract (50%) of the roots on oral administration was found to stop intra-uterine contraceptive device - induced bleeding in monkeys at 50mg/kg body weight. The chloroform and methanolic extracts of the root exhibited hepato-protective activity against carbon tetrachloride induced intoxication in rats. The antihepatotoxic activity is due to the presence of rotenoids. The diuretic action of the plant may be due to the presence of beta-ecdysone.

An anti-viral agent, active against spherical and tubular viruses was isolated from the roots including systemic resistance in plants. The drug Punarnava has been reported to increase serum potential level and reduce urinary protein extraction in clinical trials in patients with nephrotic syndrome.
医学体系アーユルヴェーダ
伝統医学Katu (Pungent), Kasaya (Astringent)
潜在力Usna (Hot)
消化後の味Katu (Pungent)
病気に対する効果Dipani (digestive), Rasayana (rejuvenative)
3体液に対する効果Decreases Vata Kapha
排泄に対する効果Sara (laxative)
伝統的用法1. Paste of Punarnava (Boerhaavia diffusa), Sunthi (dry ginger) and Musta (Cyperus rotundus) should be taken in dose of 10 gm with milk 640 ml for anaemia/anemia.

2. The vegetable of Punarnava is particularly efficacious in oedema.

3. Decoction or paste of the root of Punarnava mixed with Sunthi should be taken followed by intake of milk for a month.

4. Ghee cooked with decoction and paste of Punarnava alleviates oedema.

5. Guggulu taken with decoction of Punarnava, Devadaru (Cedrus deodara) and Sunthi alleviates oedema.

6. Punarnava, Guduci (Tinospora cordifolia) and Guggulu (Commiphora wightii) pounded in equal quantity alleviates oedema, intestinal colic, ascitic disorders and disorders of Kapha.

7. Decoction of Punarnava and Varuna (Crataeva nurvala) alleviates internal abscess.

8. Milk cooked with Punarnava should be taken for calculus.

9. Punarnava removes itching, discharge, corneal opacity, defects of vision and night blindness taken with milk, honey, ghee, oil and sour gruel respectively.

10. Pounded with roots of white Girikarnika (Clitoria ternatea) and Punarnava mixed with Barley powder and dissolved in water are filled in the eye. It removes corneal opacity.

11. Decoction of Punarnava, Devadaru and Murva (Marsdenia tenacissima) mixed with honey should be taken.

12. One who takes paste of fresh Punarnava with milk for fortnight, six months or a year is rejuvenated.

13. Red rice cooked with Punarnava powder, sugar, Juice of Draksa (grapes), milk and ghee should be taken by one suffering from haemoptysis/hemoptysis.

14. Milk boiled with Vrsciva (Boerhavia verticillata), Bilva and Punarnava along with water reduced to milk only alleviates all types of fever.

15. Decoction of Punarnava induces sleep.

16. Paste of Sati and Sunthi taken with decoction of Punarnava for a week alleviates rheumatic fever.

17. Root of Punarnava cooked with rice along with Kalasaka (Murraya koenigii), salt and Sunthi and mixed with ghee removes pain of intestinal tumour/tumor immediately.

18. Pain in vagina is relieved by putting juice of Punarnava into the vagina.
方剤Punarnavadi kvatha, Punarnavasava, Punarnavamandura, Punarnavastaka, Punarnavadyarista, Punarnavadya taila
同類生薬Trianthema portulacastrum L.
コメントAnother variety is called Sveta mula, Mandalapatraka, Svetapatra, Amlasaka, Vaisakha, Virecani, Kathilla, Mahavarsabhu, Vrsaketu, Sophaghni, Dirghapatrika, Prthvi, Sitavarsabhu. Yet another variety blue in colour according to Raja nighantu is Nila, Syama, Nilapunarnava, Krsnakhya, Nilavarsabhu, Nilini. White and red varieties are slightly different in quanlities.

This is included in Vayasthapana, Kasahara, Svedopaga, Anuvasanopaga gana of Caraka and Vidarigandhadi of Susruta.
参考文献参考図書 

Tips!

[2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras)
Vol. 1 (Repr.1996), pp 281-285.

Glossary of Indian Medicinal Plants, 1956. Chopra, R.N., Nayar, S.L. and Chopra, I.C., Council of Scientific & Industrial Research, New Delhi. - New Edition (1996) National Institute Science Communication; Supplement
p 39.

Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi
p 84.

Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi
pp 387-390.

The Ayurvedic Pharmacopoeia of India, Part I, Vol I, Ed. I, 1989. Govt. of India, Ministry of Health & Family Welfare, Dept. of Health, New Delhi
pp 95-96.

Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore
251.

Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi
Vol. 2, p 630.

Classical uses of Medicinal Plants, 1996. Sharma, P.V., Chaukhambha Visvabharati, Varanasi
p 248.

研究論文一覧*C1 Gupta, D. R. and Ahmad, B.; Ind. J. Chem., 23B, 682 (1984).
*C2 Ahmad, B. and Yu, C. -P., Phytochemistry, 31, 4382-84 (1992).
*C3 Kadota, S., Lami, N., Tezuka, Y. and Kikuchi, T.; Chem. Pharm. Bull., 36, 834-36 (1988).
*C4 Gupta, J. and Ali, M.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem., 37B, 912-17 (1998).
*C5 Srivastava, R. and Shukla, Y. N.; Indian Drugs, 35, 103-4 (1998).
*C6 Wahi, A. K., Agrawal, V. K. and Gupta, R. C.; Natl. Acad. Sci. Lett. (India), 20, 119-23 (1997).
*C7 Kadota, S., Lami, N., Tezuka, Y. and Kikuchi, T.; Chem. Pharm. Bull., 36, 2289-92 (1988).
*C8 Lami, N., Kadota, S., and Kikuchi, T.; Chem. Pharm. Bull., 39, 1863-65 (1991).
*C9 Jain, G. K. and Khanna, N. M.; Indian J. Chem., Sect. B, 28B, 163-66 (1989).
*C10 Kadota, S., Lami, N., Tezuka, Y. and Kikuchi, T.; Chem. Pharm. Bull., 37, 3214-20 (1989).
*C11 Lami, N., Kadota, S., Tezuka, Y. and Kikuchi, T.; Chem. Pharm. Bull., 38, 1558-62 (1990).
*C12 Seth, R. K., Khanna, M., Chaudhary, M., Singh, S. and Sarin, J. P. S.; Indian Drugs, 23, 583-84 (1986).
*C13 Lami, N., Kadota, S., Kikuchi, T. and Momose, Y.; Chem. Pharm. Bull., 39, 1551-55 (1991).
備考The herb is a constituent of a new herbal composition - Herbo rheumal - which shows antiinflammatory and analgesic properties comparable with that of placebo and ibuprofen. The plant is also an ingredient of a herbal eye drop preparation which has been reported to be more efficacious in patients suffering with viral keratitis. Fruit decoction has been recommended as a cure for arthritis.

The market samples of Punarnava are often adulterated with Trianthema portulacastrum L. (also often referred to as Sveta punarnava) which has led to controversy as to the correct identity of Punarnava. It has now been proved that the two plants are the sources of two different Ayurvedic drugs Punarnava and Varsabhu possibly with similar therapeutic effects.
更新日2023/12/26