Crude drug sample data base
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Crude drug name | Market name | Babchi |
|---|---|---|
| Formal name | Bakuci | |
Other names Tips！ | Baabchi (T), Bakuchidaanaa (B), Baabchi (H), Bavanchigida (K), Karkokilari (M), Baavanchalu (Te), Kaarboka arisi (Ta), Somaratsaa (Ti), Bodi (Sin) | |
| English name | Psoralea Seed | |
| Original plant name | Psoralea corylifolia Linn., Psoralea Seed | |
| Family name | Leguminosae | |
| Used part | Classification | Plant origin | Sub classification | fruit |
| Production area information | India | |
| Collection information | India, Dibrugarh, Assam , Shree Vishwanath Marwari Databye Aushadhalaya | |
| Collection date | 1997/05/05 | |
| Collector | Katsuko Komatsu, et al. | |
| TMPW No. | 17319 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
Production area information
India
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27.4728327
94.91196209999998
Collection information
India,Dibrugarh, Assam
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Scientific information data base
| Crude drug name | Ayurvedic name or Sanskrit name, English name | Bakuci, Psoralea Seed | |||
|---|---|---|---|---|---|
| Synonyms | Krsnapuspa, Gucchaphala, Durgandha, Krsnabijaka, Avalguja, Aja, Bakucika, Puriphala, Krsnaphala, Somalata, Sasankarekha, Induraji, Somaraji, Suparnika, Sasilekha, Soma, Putaphala, Somavalli, Kalamesi, Kusthaghni, Suvallika, Sita, Sitavari, Candralekha, Candri, Suprabha, Kusthahantri, Kambhoji, Pratigandha, Candrabhidha, Raji, Kalmasi, Aindavi, Kusthadosaha, Kantida, Putikarni, Durgandha | ||||
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| Original plant name | Psoralea corylifolia Linn. | ||||
| Family name | Leguminosae | ||||
| Used part | Fruits | ||||
| Distribution area | Almost throughout India reported to be cultivated in the eastern districts of Punjab adjoining Uttar Pradesh and in Rajasthan. | ||||
| Remarks | Common. | ||||
| Common uses | Fruits (seeds) are laxative, aphrodisiac, anthelmintic, diuretic and diaphoretic in febrile conditions. They are used in the treatment of haematemesis/hematemesis, leprosy, leucoderma, erysipelas, bilious affections and skin diseases. They are prescribed both for oral administration and for the local external application in the form of a paste or ointment for leucoderma. The use of fruits (seeds) in leprosy has been more or less abandoned. | ||||
| Therapeutic uses | Raktapitta (bleeding disorders), Kustha (skin diseases), Krmi (worms), Svasakasa (respiratory disorders), Meha (diabetic types), Jvara (fever), Vrana (wounds), Visa (poison), Kandu (itching) | ||||
| Chemical constituent | Seeds (fruits) contain an essential oil(0.05%), terpenoid oil(non-volatile), a dark brown resin(8.6%), a monoterpenoid phenol named bakuchiol, a brown fixed oil(c10%), raffinose and coumarin compounds, i.e., psoralen, isopsoralen, psoralidin, isopsoralidin and corylifolin; corylifonol, isocorylifonol, bakuchicin, angelicin, corylifolinin, p-hydroxybenzoic acid, astragalin and stigmasterol. | ||||
| Pharmacological effect | Clinical trials conducted in India have shown that the fruits (seed) and their various preparations are useful in the treatment of leucoderma of non-syphilitic origin. Psoralen and isopsoralen are considered the therapeutically active constituents of the fruits (seeds). The drug appears to have a purely local action with specific effect on arterioles of the subcappillary plexesus which are dilated so that plasma is increased in this area. The skin becomes red and the melanoblasts(pigment-forming cells) are stimulated. In leucoderma the melanoblasts do not function properly and their stimulation by the drug leads them to form and exude pigments which gradually diffuse into the white leucodermic patches. The treatment by this drug has not been effective in the leucoderma of syphilitic group, because in such cases, in all probability, the melanoblasts are killed, for they are not visible in the histological preparations. A number of preparations have been tried in numerous cases of leucoderma and other skin diseases. Oral administration of the powdered seeds to the patients has generally resulted in side reactions such as nausea, vomiting, malaise, headache and sometimes purging. External application of the essential oil preparations generally proved to be highly irritant to the skin causing sensitiveness and even blistering. Intra-dermal injection of the oil, though effective was normally accompanied by severe pain with a tendency to ulceration. Local application of the oleoresinous extract of the seeds (fruits) has been recommended as a more suitable preparation. The extract is official in I.P as Babchi ointment or Application of Psoralea. The strength of the oil or oleoresin preparation should be so adjusted as not to allow its action to go beyond the state of redness of the leucodermic patches. The use of these preparations has however not resulted in permanent cure. There has been even total failure in some cases. Trials with active principle, psoralen and isopsoralen mixture given orally have shown that this treatment has some value which is not obtainable by external application of the oil or the oleoresinous extract. In trials with patients aged below 20 and having leucoderma of recent origin, encouraging results were obtained with the furocoumarin mixture. External application of a liquid preparation made from this mixture was also tried on white patches simultaneously with oral administration. The patches tended to be covered up gradually and the initial time of response varied between 10 and 30 days. No fresh patches appeared during the course of the treatment and relapses were few. Processes for the extraction of psoralen-isopsoralen mixture from the seeds have been developed and covered by patents. The furocoumarins are present in the fresh seeds as glycosides of the corresponding coumarinic acids and cannot be fully extracted out directly. Soaking the ground seeds in water for a few days prior to extraction, hydrolyses the glycosides thereby releasing the coumarins. Yields upto 1% of the mixture have been obtained. Psoralen is reported to be more potent than other furocoumarins like xanthotoxin and bergapten. The essential oil shows a selective activity against the skin streptococci and this is probably the reason for its use in the indigenous medicine for skin diseases. The oil has a distinct stimulant action on voluntary muscles in high dilutions upto 1 in 100,000. It increases the tone of the uterus and stimulates the intestinal smooth muscles of the experimental animals. Psoralen may be an effective agent for the treatment of human mucoepidermoid carcinoma. The combination therapy of psoralen and UV Irradiation has been shown to Inhibit the growth of the tumours in vivo and MB, HeLa, S-180 and H-22 cells in vitro. Bavachinin-A, a flavanone isolated from the fruits revealed marked anti-inflammatory, antipyretic and mild analgesic properties at a dose of 25-100mg/kg. Oral administration of bavachinin had effects similar to that of oxyphenyl butazone and hydrocortisone. It (50mg/kg P.O.) has demonstrated better anti-pyretic activity than paracetamol (250mg/kg P.O.). In view of the promising pharmacological activities and lack of acute toxicity, it is apparent that bavachinin has a potential for therapeutic activity. | ||||
| Medical system | Ayurveda (Traditional Indian medicine) | ||||
| Traditional concept | Rasa (Taste) | Katu (Pungent), Tikta (Bitter), Madhura (Sweet), Kasaya (Astringent) | |||
| Virya (Potency) | Sita (Cold) | ||||
| Guna (Quality) | Ruksa (Dry), Laghu (Light) | ||||
| Vipaka (Post digestive taste) | Katu (Pungent) | ||||
| Karma (General action) | Rasayana (rejuvenative), Balya (strengthening), Medhya (good for intellect), Dipana (increasing digestive fire), Vistambhahrt (removes blocks) | ||||
| Dosakarma (Action on dosa) | Decreases all three dosas | ||||
| Mala (Action on excretory mechanism) | Grahi (constipative) | ||||
| Avayava (Action on organ) | Hrdya (good for heart), Tvak (skin) | ||||
| Traditional usage | 1. Bakuci (Psoralea corylifolia) seeds are taken with hot water for 21 days for skin diseases. One should consume milk along with this. Similarly Bakuci should be taken with warm water and the patient be exposed to the sun keeping on milk diet. Thus gets rid of the skin diseases. 2. Decoction of Bakuci is taken for elephantiasis. 3. One should use Tuvaraka (Hydnocarpus laurifolia) seeds, Bhallataka (Semecarpus anacardium), Bakuci, Citraka (Plumbago zeylanica) root and Silajatu (Asphalt) according to the method of rejuvenation. 4. An ointment with the powder of Bakuci mixed with Sunthi (dry ginger) destroys severe and chronic skin disease. 5. Bakuci seeds with Haritala (orpiment) pounded with cow's urine restores normal colour in vitiligo. 6. Decoction of Amalaka (Phyllanthus emblica) and Khadira (Acacia catechu) added with Bakuci powder should be used regularly keeping on wholesome diet. It alleviates vitiligo. 7. Bakuci is put in decoction of Bibhitaki (Terminalia bellirica) bark overnight, then pounded taken with oil. It destroys vitiligo and skin diseases. 8. Milk is curdled in an earthen vessel pasted inside with the powder of Bakuci. Ghee extracted from this should be taken with honey followed by intake of buttermilk. It destroys vitiligo. 9. Intake of Tila (Sesamum indicum) with Bakuci daily destroys ring worm. 10. Gruel cooked with Bakuci is useful in poisoning. 11. A woman taking Bakuci with ghee along with warm water in menstrual period keeping on diet with milk processed with Asvagandha (Withania somnifera) gets male progeny. 12. Leaves of Bakuci cooked with curd and pomegranate and added with ample ghee are used as vegetable. 13. Roots of Bijapura (Citrus medica) and Bakuci in equal quantity are pounded and made into a pillet. It is pressed under the teeth which relieves pain in caries. 15. One should take powder of Musali (Curculigo orchioides) and Bakuci in treatment of deafness. 16. Decoction of Bakuci destroys filaria. 17. Application of the paste of Bakuci checks haemorrhage in wounds. | ||||
| Formulation | Avalgujabijadi curna | ||||
| Comments | Fruits is pungent, increase Pitta and reduces Kapha Vata, good for hair, skin diseases, vomiting, respiratory disorders, oedema, anaemic/anemic conditions. There are two varieties of Bakuci according to Susruta samhita. They are Sveta and Krsna. | ||||
| References | Reference book Tips！ | [2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras) Vol. 4 (Repr.1997), pp 374-378. Glossary of Indian Medicinal Plants, 1956. Chopra, R.N., Nayar, S.L. and Chopra, I.C., Council of Scientific & Industrial Research, New Delhi. - New Edition (1996) National Institute Science Communication; Supplement p 206. Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi p 208. Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi p 69. The Ayurvedic Pharmacopoeia of India, Part I, Vol I, Ed. I, 1989. Govt. of India, Ministry of Health & Family Welfare, Dept. of Health, New Delhi p 25. Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore 1360. Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi Vol. 2, pp 175 - 178. Classical uses of Medicinal Plants, 1996. Sharma, P.V., Chaukhambha Visvabharati, Varanasi p 264. | |||
| Last renewal date | 2023/12/08 | ||||
