Crude drug sample data base
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Crude drug name | Market name | Kamila |
|---|---|---|
| Formal name | Kampillaka | |
Other names Tips！ | Kamila, Kamala powder (T), Kamalaguri (B), Kamila (H), Chandrahittu (K), Tavitu, Kampippala (M), Kamilapodi (Te), Kamelamavu (Ta), Kabilayaka (Ti) | |
| English name | Kamala Powder | |
| Original plant name | Mallotus philippensis (Lam.) Mull.-Arg., Kamala Powder | |
| Family name | Euphorbiaceae | |
| Used part | Classification | Plant origin | Sub classification | others |
| Collection information | India, New Delhi , Hans Raj & Sons | |
| Collection date | 1991/05/07 | |
| Collector | Tsuneo Namba, et al. | |
| Remarks | Used part is its dried glands covering mature fruits. | |
| TMPW No. | 12482 | |
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Production area information
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Collection information
India,New Delhi
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Scientific information data base
| Crude drug name | Ayurvedic name or Sanskrit name, English name | Kampillaka, Kamala Powder | |||
|---|---|---|---|---|---|
| Synonyms | Candrikadhya, Alparecana, Istikacurnasamkasa, Saurastradesavrksa, Pusparenu, Rajanika, Recanaka, Ranjaka, Ranjanaka, Raktanga, Manohva, Curnaphala, Lohitaksa, Karakasa, Candra, Raktacurnaka, Lohitanga | ||||
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| Original plant name | Mallotus philippensis (Lam.) Mull.-Arg. | ||||
| Family name | Euphorbiaceae | ||||
| Used part | Glandular hair of the fruit | ||||
| Distribution area | Throughout tropical India along the foot of Himalayas, from Kashmir eastwards, upto 1500m altitude and all over Bengal. | ||||
| Remarks | Common. | ||||
| Common uses | The drug is bitter, anthelmintic, cathartic and styptic. It is commonly used in the treatment of tapeworm infestation in cattle and other livestock. Kamala is used in external applications for parasitic affections of the skin, such as scabies, ringworm and herpes and is reported to possess lithontriptic properties. Kamala powder possesses purgative properties and in full doses occasionally causes nausea. | ||||
| Therapeutic uses | Krmi (worms), Gulma (intestinal tumours/tumors), Gara (a type of poison), Meha (daibetic types), Udara (asctic types), Vrana (wound), anaha (abdominal distension), Asma (calculi), Vibandha (blocks), Vatasra (arthritic conditions), Rakta gulma (uterine tumour/tumor) | ||||
| Chemical constituent | Flavanones & Dihydroflavonols Mallotus B (*C2), Isoallorottlerin (*C2), 2,3-Dihydro-5,7-dihydroxy-6-methyl-8-(3-methyl-2-butenyl)-2-phenyl-4H-benzopyran-4-one (*C2), 2,3-Dihydro-5-hydroxy-6,8,8-trimethyl-2-phenyl-4H,8H-benzo[1,2-b:3,4-b’]dipyran-4-one (*C2) Chalcones, Dihydrochalcones & Aurones Mallotus A (*C2), 1,9-Epoxy-6H-dibenzo[b,d]pyran, 2-propen-1-one derive (*C2), 2,3,9,10-Tetrahydro-5-hydroxy-6,8,8-trimethyl-2-phenyl-4H,8H-benzo[1,2-b:3,4-b’]dipyran-4-one (*C2), 10-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-3,4,7,8-tetrahydro-5-hydroxy-2,2-dimethyl-8-phenyl-2H,6H-benzo[1,2-b:5,4-b’]dipyran-6-one (*C2), 3-Phenyl-1-(5,7,8-trihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-2-propen-1-one (*C2), 1-(5,7-dihydroxy-2,2,6-trimethyl-2H-1-benzopyran-8-yl)-3-phenyl-2-propen-1-one (*C2), 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-phenyl-2-propen-1-one (*C2) Phloroglucin derivatives Mallotophilippen A (*C1), Mallotophilippen B (*C1), Rottlerin (*C2) | ||||
| Pharmacological effect | The activity of the drug as a purgative is attributed to rottlerin and iso-rottlerin the latter being slightly more active; a 1:1 mixture of the two is more active than either of them alone. Kamala possesses pronounced inhibitory action on succinic dehydrogenase of tapeworm and is considered effective as a taenifuge. Oral administration in the form of emulsions reduces fertility in female rats and guinea pigs. The effect however, is temporary as the animals return to normal after the drug is withdrawn. The anti-fertility factor is rottlerin, iso-rottlerin is feebly active, if at all. A suggested method for assaying the drug in commercial samples is based on its toxicity to fish-Hyplochilus panchax. | ||||
| Medical system | Ayurveda (Traditional Indian medicine) | ||||
| Traditional concept | Rasa (Taste) | Katu (Pungent) | |||
| Virya (Potency) | Usna (Hot) | ||||
| Guna (Quality) | Laghu (Light), Ruksa (Dry), Tiksna (Sharp) | ||||
| Vipaka (Post digestive taste) | Katu (Pungent) | ||||
| Karma (General action) | Vranasodhana (clearing wound), Agnikara (increasing digestive fire) | ||||
| Dosakarma (Action on dosa) | Decreases Kapha, Pitta | ||||
| Dhatukarma(Action on body tissues) | Asra (blood) | ||||
| Mala (Action on excretory mechanism) | Recana (laxative) | ||||
| Traditional usage | 1. The powder of Kampilla (Mallotus philippensis) taken along with Jaggery is good for intestinal worms. 2. In "Gulma" (intestinal phantom tumours/tumors) caused by pitta, one should take extract of Draksa (raisins) and Haritaki (Terminalia chebula) mixed with jaggery or Kampilla mixed with profuse honey in order to induce purgation. 3. In "Raktagulma" (uterine tumour/tumor), the powder of Kampilla mixed with sugar and honey should be given which also eliminates faeces. 4. One suffering from diabetic types caused by Kapha and Pitta should take powdered flowers of Kampilla, Saptaparna (Alstonia scholaris), Sala (Shorea robusta), Bibhitaki (Terminalia bellirica), Rohitaka (Tecoma undulate), Kutaja (Holarrhena pubescens) and Kapittha (Feronia limonia) mixed with honey or the paste thereof in the dose of 10gm with the juice of Amalaka (Phyllanthus emblica). 5. Oil cooked with Durva (Cynadon dactylon) juice or Kampillaka or the paste of Daruharidra (Berberis aristata) bark is an efficacious would healing. | ||||
| Formulation | Jivantyadi yamakam, Krmighatini vatika | ||||
| Comments | The leaves are cold, bitter, constipative and digestive. Synonym Alparecana means mild laxitive action, istikacurnasamkasa means the powder colour as that of clay powder. Saurastradesaja means its availability in Saurastra. Pusparenu denotes the hair of fruit. Rajanika and Ranjanaka denote the colouring property. Raktanga, Lohitaksaka, Raktacurna, Lohitanga indicate the red colour. This is included in Virecanagana of Caraka and Adhobhagahara and Syamadi gana of Susruta. | ||||
| References | Reference book Tips！ | [2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras) Vol. 3 (Repr.1996), pp 375-379. Glossary of Indian Medicinal Plants, 1956. Chopra, R.N., Nayar, S.L. and Chopra, I.C., Council of Scientific & Industrial Research, New Delhi. - New Edition (1996) National Institute Science Communication; Supplement p 160. Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi p 254. Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi p 203. The Ayurvedic Pharmacopoeia of India, Part I, Vol I, Ed. I, 1989. Govt. of India, Ministry of Health & Family Welfare, Dept. of Health, New Delhi p 55. Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore 1060. Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi Vol. 2, pp 521-523. Classical uses of Medicinal Plants, 1996. Sharma, P.V., Chaukhambha Visvabharati, Varanasi p 81. | |||
| Research paper | *C1 Daikonya, A., Katsuki, S., Wu, J.-B. and Kitanaka, S., Chem. Pharm. Bull., 50, 1566-69 (2002). *C2 Ahluwalia, V. K., Sharma, N. D., Mittal, B. and Gupta, S. R., Indian J. Chem. Sect. B, 27B, 238-41 (1988). | ||||
| Last renewal date | 2023/12/21 | ||||
